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KRAS Biomarkers

News and reporting on KRAS biomarkers.

Anagnostics said this week that it has tapped fellow Austrian firm Vela Laboratories to be its first service partner. Vienna-based Vela will now offer its pharmaceutical and biotech clients the ability to use Anagnostics' cylindrical HybCell microarray platform.

Express Scripts is the only one out of the big three PBMs that hasn't yet made an acquisition to directly support a personalized medicine focus. However, the firm has expressed an interest in applying PGx strategies to rein in healthcare costs, and acquiring Medco would bring it such capabilities.

Following a positive recommendation from the EMA committee, the European Commission is expected to issue a decision in September regarding marketing Tarceva as a first-line treatment for EGFR-mutation-positive NSCLC.

Product Watch: Apr 14, 2011

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Life Tech's Ion OneTouch system; Transgenomic's Surveyor Scan BRAF and PIK3CA mutation-detection kits.

PGXL will use AutoGenomics' Infiniti analyzer for various personalized medicine applications. Specifically, PGXL plans to use AutoGenomics' FDA-cleared Infiniti warfarin assay and CYP450 2C19 assay.

An expanded license with Dana-Farber Cancer Institute for an offshoot of its Cold-PCR technology allows Transgenomic to develop kits that can detect mutations in common cancer-related genes such as KRAS and P53 directly from blood samples and then analyze the variants using multiple sequencing approaches.

"With genomics, and pharmacogenomics, and all the other aspects of the cancers, we have to think of a different way than the randomized trial," said Patrick Loehrer, interim director of Indiana University's cancer center and a member of FDA's Oncology Drugs Advisory Committee.

The protocol for the trial, which will study overall survival in Vectibix-treated chemorefractory patients with wild-type KRAS tumors, is currently being reviewed by the FDA.

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Researchers have developed a robotic lab assistant, the Verge reports.

CBC News reports Canada's Supreme Court is to rule on the constitutionality of the country's genetic non-discrimination law today.

The Associated Press reports the World Health Organization is sending experts to China to investigate the animal source of SARS-CoV-2.

In Science this week: atlas of affected cell populations in idiopathic pulmonary fibrosis, and more.