IVF Embryo Selection From Polygenic Risk Scores Enters Market as Clinical Value Remains Unproven Premium Companies are entering the human reproduction field with embryo tests claiming to help minimize genetic risk for a host of complex diseases. Low, Medium Levels of Mosaic Aneuploidy Among Embryos Don't Affect Birth Rates, Study Finds An Igenomix-led team finds that low- or medium-grade mosaic embryos have similar birth and miscarriage rates as euploid embryos among IVF patients. Menopause Timing Influenced by Hundreds of Genetic Loci, New GWAS Finds The findings, from an analysis of more than half a million women, could eventually be used to avoid or improve fertility treatments, according to the researchers. Thermo Fisher Scientific, First Genetics to Develop NGS-Based Diagnostics in Russia First Genetics will market its F-Genetics NGS System and IVD assays to Russian laboratories for reproductive health testing and cancer diagnostics. IVF Doesn't Increase Chromosomal Instability in Newborns, Study Finds An analysis of placental, parental, and cord blood samples indicated that an uptick in chromosomal instability in cleavage-stage in vitro fertilization embryos does not persist after birth. Jan 31, 2019 Genomic Prediction Raises $4.5M Aug 30, 2018 Celmatix, Ferring Pharmaceuticals Partner to Study Genomics of IVF Treatment Response Mar 27, 2018 Columbia University Team Develops Nanopore Method for Preimplantation Genetic Screening Premium Jul 14, 2017 New Study Bolsters View That Mosaic Embryos From IVF Can Develop Into Healthy Babies Premium Jul 7, 2017 Preimplantation Genetic Screening Has Transformed Practice of IVF Clinic, but Cost Remains Barrier Premium Jun 16, 2017 Combining PGD and PGS to Select Embryos Increases Pregnancy Rate But Results in Fewer Transfers Premium Apr 26, 2016 CombiMatrix Gets Serious About Potential M&A Options in Wake of $8M Offering Premium Mar 4, 2016 Episona Finishing Validation of Epigenetic Male Fertility Test With Eye on Q3 Launch Premium Dec 28, 2015 Harvard, Peking University Team Combines NGS, Linkage Analysis to Detect Aneuploidy, SNVs for PGD Premium Nov 5, 2015 Exome Sequencing Homes in on Gene Linked to Early Human Embryonic Lethality Feb 3, 2015 For PGS Market Entry, Agilent Draws on Dubai IVF Clinic Partnership, New 16-Plex Array Format Premium Jan 20, 2015 Reproductive Health Science Scales up Array Manufacturing to Support EmbryoCellect Test Premium Nov 10, 2014 In PGD Study, qPCR Largely Concordant with Array CGH, but May Yield Fewer False Positives Premium Aug 19, 2014 Reprogenetics Opens Miami Office to Broaden Array CGH, NGS, Karyomapping PGS Services Premium Jul 30, 2014 Illumina Mulls Investments in Array Business, Expects Long-term Growth in Consumer, Ag, IVF Markets Premium Jul 29, 2014 Reprogenetics to Adopt NGS for Pre-implantation Genetic Dx to Partially Replace 'Workhorse' CMA Premium Apr 8, 2014 Reproductive Health Science Raises $3M, Goes Public as Array-based PGS Test Nears Launch Premium Mar 26, 2014 Italian Team Validates Preimplantation Screening Method Behind Illumina's Upcoming Commercial Test Premium Feb 12, 2014 NJ Reproductive Clinic to Adopt NGS for Preimplantation Genetic Testing if Validation Trial Succeeds Premium Feb 4, 2014 Illumina's Q4 Array Sales Jump 10 Percent on Consumer Genomics, BlueGnome IVF Demand Premium Load More Breaking News New Products Posted to GenomeWeb: Qiagen, Thermo Fisher, Bionano Genomics, BillionToOne, More People in the News at Illumina Ventures, Element Biosciences, Epigenomics, Exagen, More Genomic Approaches Boost Rare Disease Diagnoses in Middle Eastern Patient Population GeneDx to Raise $150M in Public and Direct Stock Offerings In Brief This Week: T2 Biosystems, Novacyt, OpGen, Dante Genomics, Nautilus Biotechnology, More The Scan Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups. Genome-Wide Analysis Sheds Light on Genetics of ADHD A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder. MicroRNA Cotargeting Linked to Lupus A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus. Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.