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News and reporting on cancer immunotherapy.
In PNAS this week: immune gene expression differences in blood of young adults, molecular contributors to cells' microtubule and actin networks, and more.
Natera's Signatera test will be used to select and monitor eligible patients with KRAS-mutant tumors who have molecular residual disease after surgery.
Extending a prior agreement with the drugmaker, Personalis will use its DNA/RNA platform to identify both predictive biomarkers and resistance mechanisms.
In Science this week: phase I study of CRISPR-based engineering of T cells for cancer patients, call for sewage-based global antimicrobial resistance surveillance system, and more.
In Nature this week: new study of the Wuhan coronavirus suggests bats as the source of the outbreak, bioinformatic approach to identify cancer driver genes, and more.
The new center will bring together pathology, computer science, cancer genomics, and immunogenomics to study which cancer patients can benefit from immunotherapy.
Three new studies have found that the presence of B cells in tertiary lymphoid structures in tumors is associated with a favorable response to immunotherapy.
Using corrected TMB and other variables allowed Johns Hopkins researchers to more accurately predict response to immune checkpoint blockade in lung cancer.
Insight's portfolio includes a gene expression-based immuno-oncology assay for therapy response prediction.
The researchers are aiming to provide new insights as to which cancer patients will respond best to immunotherapy based on their genetic backgrounds.
NPR reports the US Food and Drug Administration has approved a treatment for a genetic disorder that causes rapid aging.
Late-stage testing indicates the AstraZeneca and Oxford University SARS-CoV-2 vaccine can have up to 90 percent efficacy, the Associated Press reports.
ScienceInsider reports Nature Communications is reviewing a paper on mentorship following social media criticism arguing it is sexist.
In PLOS this week: method to account for sequencing errors in phylogenies, study of influenza A in Switzerland, and more.