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Immunotherapy

News and reporting on cancer immunotherapy.

23andMe Looks to Advance Drug Discovery Pipeline as GSK Partnership Winds Down
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The consumer genetics firm will soon be able to team with other drug companies as it mines its genotypic database for new disease pathways.

Strata Oncology Trial Yields Novel Pan-Cancer Immunotherapy Response Predictor
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The company has derived and validated a mutational and gene expression score that predicts immunotherapy benefit across tumor types.

PamGene, Alithea Genomics, Lausanne University get €1M for Pan-Cancer Blood Test

The Dutch-Swiss Mainline consortium plans to develop a multiomics model to guide immune checkpoint inhibitor therapy across a broad range of cancers.

Texas Research Institute, TGen, OncoHost Partner to ID Lung Cancer Resistance Mechanisms

Collaborators will study the immune profiles and molecular features of NSCLC to better understand patterns of response and resistance to immunotherapy.

Esophageal Cancer Molecular Study Highlights Tumor Subtypes, Treatment Response Markers

Researchers found four esophageal squamous cell carcinoma molecular subtypes by generating genomic, transcriptomic, epigenetic, and proteomic profiles for more than 150 cases.

Dec 12, 2022

T-Cell Subpopulations in Blood May Help Predict Immune Checkpoint Immunotherapy Side Effects

Dec 7, 2022

FDA Approves Thermo Fisher HLA Typing Test as CDx for Immunocore Uveal Melanoma Therapy

Nov 30, 2022

Bladder Cancer Genomic Landscape Study Aims to Engender New Biomarker-Guided Therapies
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Nov 30, 2022

Personalis, UCSF to Study ctDNA Utility in Colorectal Cancer Treatment Response Monitoring

Nov 28, 2022

Studies Assess Tumor Aneuploidy to Guide Immunotherapy Treatment

Nov 22, 2022

Navignostics Using Single-Cell Spatial Proteomics to Guide Oncology Treatment, Drug Development
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Nov 17, 2022

Biomarker Predicts Immunotherapy Benefit in Head and Neck Cancer but Commercial Path Unclear
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Nov 16, 2022

Novigenix Raises $14M in First Closing of Series B

Nov 10, 2022

Cancer Patients in Early Trial Receive Personalized, CRISPR-Edited T-Cell Therapy

Oct 27, 2022

Immunotherapy Response Features Identified in Pancreatic Cancer Microenvironment

Oct 24, 2022

Molecular Tumor Board Therapy Matching Predicts Immunotherapy Best Responders
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Oct 4, 2022

Personalis, Duke University, Olink Collaborate on Immunotherapy Markers in Gastric Cancer

Sep 30, 2022

Tumor-Only Sequencing Found to Overestimate Mutational Burden in Non-European Patients

Sep 28, 2022

Cofactor Genomics RNA-seq Assay Outperforms PD-L1 IHC to Predict Immunotherapy Responders
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Sep 21, 2022

Propath UK, Nucleai Partner on Spatial Proteomics Panel for Immuno-Oncology

Sep 15, 2022

BriaCell, Caris Life Sciences Partner to Bolster New Immunotherapy Development

Aug 29, 2022

Combination of Genomic, Other Factors Improves Treatment Response Prediction in Lung Cancer

Aug 2, 2022

Envisagenics Wins $2M SBIR Grant From NCI for Splicing-Based Immunotherapy Target Discovery Platform

Jul 21, 2022

PamGene Gains CE-IVD Registration for Immunotherapy Guidance Tests

Jul 11, 2022

Immune Checkpoint Blockade Response Linked to Recurrent Mutations in Genes, Pathways

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The Scan

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.

Adenine Base Editor Targets SCID Mutation in New Study

Researchers from the University of California, Los Angeles, report in Cell that adenine base editing was able to produce functional T lymphocytes in a model of severe combined immune deficiency.

Researchers Find Gene Affecting Alkaline Sensitivity in Plants

Researchers from the Chinese Academy of Science have found a locus affecting alkaline-salinity sensitivity, which could aid in efforts to improve crop productivity, as they report in Science.

International Team Proposes Checklist for Returning Genomic Research Results

Researchers in the European Journal of Human Genetics present a checklist to guide the return of genomic research results to study participants.