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Human Protein Atlas

In Science this week: single-cell RNA sequencing approach to study mRNA synthesis and degradation rates, atlas of protein-coding genes in human, pig, and mouse brains, and more.

Uhlén discusses the recent Human Protein Atlas release and future plans for the project.

Scientists led by Stockholm Royal Institute of Technology (KTH) researcher Mathias Uhlén have released a new version of the Human Protein Atlas database.

Name: Peter Nilsson
Title: Platform Director, Affinity Proteomics, SciLifeLab, Stockholm

The process, which was developed through a multi-site study that produced more than 1,000 antibodies targeting 20 different SH2 domain proteins, is meant as a template for future, larger efforts and could help improve antibody validation procedures, said one of the researchers.

Researchers involved in the Human Protein Atlas project announced that they are halfway through creating a resource that will contain data on all known human proteins.

The antibodies, which Sigma-Aldrich said are the industry's most highly validated, are developed by the administrators of the Human Protein Atlas and are aimed at addressing a dearth of high-quality commercially available antibodies.

The US Food and Drug Administration is to announce stricter standards for emergency authorizations of SARS-CoV-2 vaccines, reports the Washington Post.

The Associated Press reports Johnson & Johnson is starting a late-stage clinical trial of its candidate SARS-CoV-2 vaccine.

Bloomberg reports the budget of Operation Warp Speed is actually $18 billion, higher than the number typically cited.

In Genome Research this week: genomic analysis reveals role of super-spreaders in SARS-CoV-2, epigenetic drivers of cancer, and more.