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HLA typing

CareDx's CareDx Pty subsidiary said it will pay up to $735,000 to Conexio as a percentage of revenues from products acquired in the deal. 

Under the terms of the agreement, GenDx can resell Illumina's instruments, reagents, and maintenance contracts for the field of HLA sequencing.

The contract was awarded by the UK's NHS Blood and Transplant, which is responsible for promoting and overseeing organ and blood donation.

The companies will combine Qiagen's QIAxcel and CareDx's Olerup SSP kits and Score software into an HLA typing product offering for transplant labs.

The two companies have had a years-long collaboration to develop and commercialize their NGS-based high-resolution HLA typing system.

The Dutch firm plans to develop a complete, CE-marked pipeline for NGS-base HLA typing, from DNA amplification to software analysis. 

The sequencing technology giant said its acquisition of Conexio shows its commitment to the field of transplant science and HLA technology.

The array, developed in collaboration with the International Genetics and Translational Research in Transplantation Network, is the first for transplant genomics.

The approach allowed the researchers to identify almost 300 HLA mutations overall, many of which they were able to validate using other methods.

Scientists at the Anthony Nolan Research Institute, in collaboration with Pacific Biosciences, recently published a study on typing HLA class I genes.

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