Close Menu

HLA typing

Researchers genotyped advanced cancer patients treated with immunotherapies and found that homozygosity at HLA loci was linked to decreased survival.

The kits cover the primary genetic targets currently used for assessing the compatibility of  hematopoietic cell donors with recipients.

The software provides analysis of HLA typing by NGS on several platforms, including ones from Illumina, Thermo Fisher, and PacBio.

The company said revenues from its non-invasive heart transplant rejection test AlloMap rose about 16 percent year over year.

Linkage is now part of Thermo Fisher's transplant diagnostics business, One Lambda. Linkage's flagship product line is its real-time PCR technology, LinkSeq.

In PNAS this week: sand rat genome assembly, algorithm for human leukocyte antigen typing from short-read data, and more.

In Science this week: a protective gene in C. elegans, and combining EHRs with genetic data to ID HLA-associated variants

An international team of researchers has mapped new associations between HLA mutations and specific diseases, and made their data freely accessible.

The company said revenues for the quarter and full-year 2016 included sales of Olerup HLA typing products, which CareDx got through its acquisition of Allenex.

GenDx is planning to get CE marking for an Ion Torrent-based HLA typing workflow, to add to the firm's set of NGS solutions for transplant diagnostics.

Pages

Nature News reports on how meeting cancellations and related costs are affecting scientific societies.

In a new ruling, Canada's Supreme Court upheld the country's genetic non-discrimination law, the Canadian Press reports.

COVID-19 vaccine developers aim to avoid a complication that has affected efforts to develop vaccines for other diseases, the Wall Street Journal reports.

In PLOS this week: analysis of insertions throughout Shigella genomes, antigen production in malaria parasites, and more.