HLA typing

The software provides analysis of HLA typing by NGS on several platforms, including ones from Illumina, Thermo Fisher, and PacBio.

The company said revenues from its non-invasive heart transplant rejection test AlloMap rose about 16 percent year over year.

Linkage is now part of Thermo Fisher's transplant diagnostics business, One Lambda. Linkage's flagship product line is its real-time PCR technology, LinkSeq.

This Week in PNAS

In PNAS this week: sand rat genome assembly, algorithm for human leukocyte antigen typing from short-read data, and more.

This Week in Science

In Science this week: a protective gene in C. elegans, and combining EHRs with genetic data to ID HLA-associated variants

An international team of researchers has mapped new associations between HLA mutations and specific diseases, and made their data freely accessible.

The company said revenues for the quarter and full-year 2016 included sales of Olerup HLA typing products, which CareDx got through its acquisition of Allenex.

GenDx is planning to get CE marking for an Ion Torrent-based HLA typing workflow, to add to the firm's set of NGS solutions for transplant diagnostics.

CareDx's CareDx Pty subsidiary said it will pay up to $735,000 to Conexio as a percentage of revenues from products acquired in the deal. 

Under the terms of the agreement, GenDx can resell Illumina's instruments, reagents, and maintenance contracts for the field of HLA sequencing.

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The US Food and Drug Administration has approved Kite Pharmaceuticals' CAR T-cell therapy for large B-cell lymphomas, the New York Times reports.

Kaiser Health News reports that gene therapies could cost more than a million dollars.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

In Nature this week: variants associated with obsessive-compulsive disorder, review of key CRISPR enzymes, and more.