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HLA typing

In a retrospective analysis, UK researchers found that long-read sequencing of HLA genes in stem cell transplantation donors and recipients led to better outcomes.

Japanese researchers developed a catalog of HLA alleles that they used to perform a phenome-wide association study of the MHC and about a hundred phenotypes.

The index's 13 percent gain was below the 39 percent surge of 2017 but occurred despite the poor performance of index stocks in December.

The company also said it launched a new comprehensive diagnostic called HeartCare for surveillance of heart transplant patients.

The team used genetic scoring to identify infants without a family history of the disease who had more than a 10 percent risk for developing islet antibodies.

The firm says its Olerup QType test is available on both Roche and Applied Biosystems platforms.

The workflow was cleared by the South Korean Ministry of Food and Drug Safety for the typing of HLA-A, B, C, DRB1, and DQB1 by next-generation sequencing.

The Boston-based startup wants to help individuals interpret their HLA data for ancestry and health, and participate in research studies. 

Researchers genotyped advanced cancer patients treated with immunotherapies and found that homozygosity at HLA loci was linked to decreased survival.

The kits cover the primary genetic targets currently used for assessing the compatibility of  hematopoietic cell donors with recipients.

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In a cartoon, Vox explores the lack of women among this year's winners of the Nobel Prize.

Science reports a new US defense bill would establish two groups aimed at combating foreign influence on research. 

Nature Biotechnology discusses promising early results from two clinical trials of CRISPR-based therapy for β-thalassemia and sickle cell disease.

In Cell this week: analysis of tissue clones, metagenomic studies of ocean water samples, and more.