A King's College London-led team performed a genome-wide association study of kidney transplant donors and recipients.
The Boston-based startup wants to help individuals interpret their HLA data for ancestry and health, and participate in research studies.
Researchers genotyped advanced cancer patients treated with immunotherapies and found that homozygosity at HLA loci was linked to decreased survival.
In Science this week: a protective gene in C. elegans, and combining EHRs with genetic data to ID HLA-associated variants
The approach allowed the researchers to identify almost 300 HLA mutations overall, many of which they were able to validate using other methods.
Scientists at the Anthony Nolan Research Institute, in collaboration with Pacific Biosciences, recently published a study on typing HLA class I genes.
The firm's LinkSeq test is now available in Europe for IVD applications for solid organ and stem cell transplantation.
The results provide early evidence for the ability of haplotypes in the HLA-DRB1 gene to predict outcome and drug response, which will have to be further replicated.
The researchers concluded that the technology "holds promise for clinical applications."
Biofortuna will design, develop, and manufacture a range of freeze-dried HLA-typing kits with the brand name SSPGo for Abbott's molecular diagnostics business.
In a survey, about half of Canadian government scientists say they still feel as though they cannot speak freely, ScienceInsider reports.
The Atlantic reports that biohacker Josiah Zayner regrets injecting himself with the CRISPR gene-editing tool on stage.
Clinicians in China are moving ahead with a number of CRISPR trials, NPR reports, as the US embarks on its first.
In Nature this week: genomic approaches applied to study Neolithic and Bronze Age Europeans, and more.