HLA

Linguamatics' I2E natural language processing engine helps Sanofi match HLA alleles with multiple sclerosis and associated drug treatments.

The firm said momentum from the launch of its kidney transplant test Allosure drove the overall revenue increase.

CareDx has paid Illumina a $5 million initial payment and will pay royalties in the mid-single to low-double digits on sales of future commercialized products.

A King's College London-led team performed a genome-wide association study of kidney transplant donors and recipients.

The Boston-based startup wants to help individuals interpret their HLA data for ancestry and health, and participate in research studies. 

Researchers genotyped advanced cancer patients treated with immunotherapies and found that homozygosity at HLA loci was linked to decreased survival.

This Week in Science

In Science this week: a protective gene in C. elegans, and combining EHRs with genetic data to ID HLA-associated variants

The approach allowed the researchers to identify almost 300 HLA mutations overall, many of which they were able to validate using other methods.

Scientists at the Anthony Nolan Research Institute, in collaboration with Pacific Biosciences, recently published a study on typing HLA class I genes.

The firm's LinkSeq test is now available in Europe for IVD applications for solid organ and stem cell transplantation. 

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.