Close Menu

haplotype

Sequence-level analysis of European Huntington's disease haplotype indicates its long history and suggests potential targets for allele-specific gene-targeting therapies.

The group demonstrated the ability of a genetic algorithm to gauge whether cognitively normal people are at risk of near-term mental decline.

The results provide early evidence for the ability of haplotypes in the HLA-DRB1 gene to predict outcome and drug response, which will have to be further replicated.

Their research suggests that Pinot noir clones must first mutate into Pinot gris before a second mutation turns them into Pinot blanc.

pigs

Comparing the pig genomes, the team found a large selective sweep that includes an adaptive haplotype that appears to have originated from an extinct species.

10X's approach is a synthetic long-read technology that leverages existing short-read NGS technology but fills in knowledge gaps about the human genome.

Investigators have identified a form of compound inheritance for congenital scoliosis that involves null mutations and hypomorphic alleles of a particular gene.

A team led by researchers at Washington University in St. Louis has shown that genetic variants associated with nicotine dependence and smoking quantity are also predictive of whether patients will benefit from the use of smoking cessation medications.

Researchers performed 454 amplicon sequencing on one of the most variable regions of the human genome — the beta-defensin locus — to characterize copy number variation and sequence variation.

Pages

A UK woman is suing three National Health Service Trusts for not telling her about her father's Huntington's disease diagnosis, the BBC reports.

LiveScience reports that a novel mutation in the LPL gene was uncovered in three siblings with very high triglyceride levels.

The president of Nankai University is embroiled in a data manipulation scandal, the South China Morning Post reports.

In PNAS this week: cytotoxic CD4 T cell signature in supercentenarians, evolutionary history of beetles, and more.