Childhood Epilepsy Risk Variant Traced Back to 800-Year-Old British Founder Event
A childhood epilepsy risk allele found in 14 affected families was traced back to a founder event going back 800 years that spread from Britain to other parts of the world.
Comprehensive Genealogy Spanning Modern, Ancient Humans Emerges from Large-Scale Genomic Analysis
Using a non-parametric tree-recording approach, researchers established a "genealogy of everyone" that is expected to inform human evolutionary studies.
Team Shares Chinese Genome Resource, Population Reference Panel
Researchers identified more than 79.2 million variants in Chinese individuals for the "NyuWa" resource, along with a smaller reference panel representing variants found across the country.
Arab Genome Study Improves Understanding of Migration Patterns, Haplotype Imputation
The researchers built a reference panel of 12,432 haplotypes, improving genotype imputation for both rare and common alleles in Arabs and the wider Middle East.
Study Spells Out Separate Parental, Fetal Genome Contributions to Fetal Growth
With the help of phased Icelandic genomes, researchers found fetal growth-associated variants in maternal, paternal, and fetal genomes, including some with opposite effects on growth.