GWAS

A large genome-wide association study that included more than 400,000 UK Biobank participants led to 69 new or known loci associated with 25-hydroxyvitamin D levels.

The new PRS could help identify people at increased risk who may benefit from earlier screening and treatment to prevent blindness.

A genome-wide association study uncovered six loci associated with heavy drinking and additional analysis found ties to other conditions including lung cancer.

A genome-wide association meta-analysis involving almost one million heart failure cases and controls identified 11 risk loci and helped distinguish potential causal contributors.

Some of these shared loci were associated with higher BMI, but some were linked to lower BMI, particularly those also linked to schizophrenia.

A genome-wide association study involving some 200,000 veterans unearthed five anxiety risk loci in European Americans and another risk locus in African Americans.

New research suggests that a set of common variants on chromosome 22 may influence heart defects associated with a condition called 22q11.2 deletion syndrome.