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GWAS

Using array-based genotyping profiles for COVID-19 cases and controls, researchers identified loci on chromosomes 3 and 9 that are linked to cases with respiratory failure.

A meta-analysis including 1.4 million people from five ancestral groups identified 318 novel variants associated with type 2 diabetes and related vascular outcomes.

Researchers from startup Duality Technologies and Dana-Farber have demonstrated the efficacy and speed of a highly secure technique for analyzing encrypted genomic data.

In PLOS this week: genome-wide association study of agronomic traits in sugarcane, breastfeeding can modulate body-mass index among individuals at genetic risk of obesity, and more.

In Nature this week: genome-wide association study of 42 diseases among Japanese population, transfer RNA modifications, and more.

Polygenic risk scores have the potential to impact cancer screening, autoimmune disease testing, and therapeutics development, but more diverse data is needed.

The GWAS of more than 200,000 Japanese individuals across 42 diseases identified 25 novel loci shared between Japanese and European populations.

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A genome-wide association study has uncovered patient variants linked to COVID-19 severity, The Scientist reports.

In PLOS this week: gene expression and epigenetics of Indonesian populations, hookworm parasite secretome, and more.

In Nature this week: the largest known collection of human genetic variants, and more.

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New analyses indicate the P.1 variant found in Brazil may be able to infect people who have already had COVID-19, the New York Times reports.

According to CNBC, Novavax's CEO says its vaccine could be authorized in the US as early as May.

The US National Institutes of Health has a new initiative to address structural racism in biomedical research.

In PNAS this week: GWAS of TLV-1-associated myelopathy/tropical spastic paraparesis, analysis of twins with hypertrophic cardiomyopathy, and more.