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By uncovering genetic factors behind blood and urine biomarkers, researchers came up with polygenic scores related to biomarker status and related disease risk.
The findings further suggested the gut microbiome could influence conditions like inflammatory bowel disease and serve as therapeutic targets.
In Science this week: analysis of genome-wide association studies of chronic kidney disease, and more.
The researchers developed an approach to mitigate the effects of misreporting or longitudinal changes in drinking behavior.
In Genome Biology this week: loci linked to longitudinal pediatric bone accrual, role of complement cascade gene in pancreatic cancer metastases, and more.
In a genome-wide association study of Takayasu arteritis, researchers uncovered disease-linked loci both within and beyond the HLA region.
Researchers identified several immune-related genes in a GWAS that included more than 2,200 COVID-19 patients treated in UK intensive care units.
The study, which focused on Europeans, also highlighted a role for enhancers during embryonic development in determining facial features.
In PLOS this week: somatic mutation patterns of glioblastomas among Lebanese patients, phenome-wide study using UK Biobank data, and more.
Exome array-wide association and rare variant-focused genome-wide association meta-analyses led to 87 rare variants with ties to one or more blood pressure traits.
New analyses indicate the P.1 variant found in Brazil may be able to infect people who have already had COVID-19, the New York Times reports.
According to CNBC, Novavax's CEO says its vaccine could be authorized in the US as early as May.
The US National Institutes of Health has a new initiative to address structural racism in biomedical research.
In PNAS this week: GWAS of TLV-1-associated myelopathy/tropical spastic paraparesis, analysis of twins with hypertrophic cardiomyopathy, and more.