Using data for nearly 45,000 epilepsy cases and controls, researchers identified loci contributing to focal epilepsy, genetic generalized epilepsy, or unclassified epilepsy.
Researchers identified 40 new and 55 known risk variants using a GWAS meta-analysis that included low-frequency variants gleaned from genome sequence data.
A GWAS meta-analysis involving hundreds of thousands of cases and controls led to new and known gallstone disease-associated variants at 28 loci.
Research presented at AMIA this month demonstrated a computing method for predicting family pedigrees by mining demographic data in electronic health records.
Genome-wide association and meta-analyses have uncovered a dozen ADHD-related loci, providing insights into its biology and overlap with other conditions.
A gene-environment analysis involving 10,346 twins suggests parents are more restrictive when feeding children who have a genetic propensity for weight gain.
A Mendelian analysis hints that variants implicated in bitter taste perception may affect a person's preference for coffee, tea, and/or alcohol.
GWAS summary statistics data led to three main loci with ties to both Alzheimer's and cardiovascular disease, with additional enrichment at lipid-related sites.
At least some variants associated with benign prostatic hyperplasia appeared to contribute to PSA levels in the blood, independent of prostate cancer.
With genome-wide association studies involving more than 200,000 individuals, researchers narrowed in on 58 loci and dozens of genes with ties to a chronic infection marker.
Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.
The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.
ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.
In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.