GWAS | GenomeWeb

GWAS

A genome-wide association study and meta-analysis uncovered several possible ties to multiple keratinocyte cancer versus single keratinocyte cancer cases.

Based on genetic patterns in thousands of individuals with primary sclerosing cholangitis, researchers identified four new risk loci and explored ties to IBD.

The project is the consumer genomics firm's latest effort to improve diversity in genetics research. 

The company hopes to sequence about 60,000 whole genomes, and genotype 100,000 individuals to accelerate clinically relevant discoveries.

Researchers uncovered 60 genomic loci associated with birth weight and found that those regions are also linked to risk for type 2 diabetes and other diseases.

Italian researchers link SNPs in the PDSS2 gene to coffee consumption in a new paper.

The method works by adding noise to database search results to confound algorithms that try to access private details about contributing individuals.

The study confirmed 17 previously identified loci, and uncovered 14 new ones that researchers hope can improve understanding of BCC pathogenesis and inform strategies for prevention.

The health system plans to incorporate a genomics risk score based on the evaluation of 300 SNPs in deciding whether patients are at a high risk for cancer.

A genome-wide association and fine-mapping study of Samoans led to a missense mutation in the CREBRF gene that seems to correspond with increased fat storage.

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In Nucleic Acids Research this week: nanopore sequencing workflow to detect antibiotic resistance in gut microbes, TSSPlant tool, and more.

Because gene-edited organisms can cross borders, Gizmodo wonders whether there should be an international body to govern their use.

HHS Secretary nominee Tom Price is to go in front of the Senate Committee on Health, Education, Labor and Pensions today, NPR's Morning Edition reports.

Prior to being closed, Theranos' Arizona lab failed an inspection by regulators, according to the Wall Street Journal.