GWAS Type 1 Diabetes GWAS, Fine-Mapping Leads to New Genetic Loci, Potential Drug Targets Starting with a large GWAS, researchers incorporated chromatin accessibility data and other clues to find key variants, immune cell types, and treatment targets. Novel Locus Tied to Rheumatic Heart Disease in Black Africans A lack of an independent cohort limited the researchers' ability to replicate their finding and underscored the need for better representation of Africans in research. GWAS Across Ancestries Uncovers Novel Genetic Loci Linked to Glycemic Traits The researchers estimated that if their analysis had only focused on individuals of European descent, they would have missed two dozen novel loci. Large-Scale Depression Genetic Study Uncovers Additional Risk Loci, Ties to Potential Drugs The analysis drew upon data from the Million Veteran Program and other large-scale efforts and underscores the genetic complexity of depression. Bipolar Disorder GWAS Meta-Analysis Points to Potential Treatment Targets Researchers identified 64 risk loci in a genome-wide association study meta-analysis that included almost 42,000 individuals with bipolar disorder. May 13, 2021 Facial Phenotyping of Siblings Helps Identify Genetic Loci Affecting Face Shape May 13, 2021 Blood Cancer Genetic Risk Loci Found in Retriever Dogs Apr 30, 2021 GWAS-Methylation Integration Could Help Identify Drug Repurposing Candidates for MS Premium Apr 21, 2021 Red Blood Cell Traits Linked to New Loci With Whole-Genome Sequencing Data Apr 16, 2021 Autoimmune Disease Risk Tied to Genetic Variation in Transcription Factor Binding Apr 15, 2021 At ACMG, Mechanism for Common Breast Cancer Locus Proposed From Functional Analysis Apr 8, 2021 GWAS Uncovers Sex-Based Differences in Genetic Origins of Chronic Pain Apr 5, 2021 Genetic Link Between Shape of Human Brain, Face Uncovered Mar 26, 2021 Low-Coverage Sequencing Effectively IDs Novel Variants in Underrepresented Populations Mar 15, 2021 Gene Screening Tool Allows Researchers to Zero in on Variants Influencing Lupus Risk Mar 8, 2021 Case-Case GWAS Approach Identifies Loci That Differ in Frequency Across Psychiatric Disorders Feb 24, 2021 Glaucoma GWAS Meta-Analysis Uncovers New Risk Loci, Shared Risk Across Ancestry Groups Feb 9, 2021 Germline Genetic Variants May Influence Tumor Immune Microenvironment, Treatment Response Feb 5, 2021 GWAS of Latin Americans Suggests Lip Shape Influenced by Locus of Denisovan Origin Jan 28, 2021 Million Veteran Program GWAS Uncovers Genetic Loci Linked to PTSD Jan 28, 2021 Alzheimer's Disease-Related Proteins Picked up in Proteome-Wide Association Study Jan 25, 2021 Hypertrophic Cardiomyopathy Studies Reveal Common Contributors, Risk Score Jan 19, 2021 Blood, Urine Biomarker Study Leads to Linked Loci, Disease-Related Risk Scores Jan 19, 2021 ABO Histo-Blood Groups Influence Makeup of Gut Microbiome, New Study Finds Jan 12, 2021 Genetic Analyses of Behavioral Traits May Be Biased Due to Misreporting, Changes in Behavior Load More Breaking News Enzo Biochem, CLX Health Partner to Support COVID-19 Testing for International Travel Type 1 Diabetes GWAS, Fine-Mapping Leads to New Genetic Loci, Potential Drug Targets LSU Health Sciences Center Wins $2.4M to Lead SARS-CoV-2 Variant Sequencing Program NanoString Technologies, Parker Institute for Cancer Immunotherapy Partner on Cell Therapy Project BGI Americas Collaborating With Champions Oncology on Proteomic Cancer Research Personal Genome Diagnostics Inks Cancer Genomic Profiling Deal with Duke University Health System The Scan Missed Early Cases A retrospective analysis of blood samples suggests early SARS-CoV-2 infections may have been missed in the US, the New York Times reports. Limited Journal Editor Diversity A survey finds low diversity among scientific and medical journal editors, according to The Scientist. How Much of a Threat? Science writes that need for a provision aimed at shoring up genomic data security within a new US bill is being questioned. PNAS Papers on Historic Helicobacter Spread, Brain Development, C. difficile RNAs In PNAS this week: Helicobacter genetic diversity gives insight into human migrations, gene expression patterns of brain development, and more.