genetic risk variants
Decode Genetics Study Unravels Complex Variant Effects on Blood Lipid Levels, Heart Disease Risk
Analyzing genetic contributors to lipid trait variance, researchers identified variant-variant and variant-environment interactions affecting coronary artery disease risk.
Blood Lipidome Profiles Linked to Aging, Health Measures in Quantitative Study
A longitudinal study linked the composition and levels of blood lipids to health, aging, viral infections, and metabolic conditions such as insulin resistance.
Esophageal Cancer Susceptibility Risk Variants Found in South African Population
Using GWAS data, researchers identified esophageal squamous cell carcinoma risk variants that overlap with those found in a high-risk population in China.
Breast Cancer Risk Genes Unearthed in Exome Sequence Meta-Analysis
Researchers tracked down a handful of previously unappreciated susceptibility genes using exome sequences for more than 244,000 European women with or without breast cancer.
Menopause GWAS Uncovers Genetic Contributors with Age-Specific Effects
A genetic analysis that focused on women's age at natural menopause uncovered hundreds of related variants, including a host of associations with effects that shift with age.