gene regulation
Neural Gene Ties, Psychiatric Disorder Clues Found Using Complex Structural Variant Detection Tool
With the help of a probabilistic, machine-learning approach called ARC-SV, researchers found and began characterizing the brain effects of complex structural variants.
Colorectal Cancer Functional Study Leads to Causal Variants, Gene Targets
Researchers relied on fine-mapping, epigenetic insights, and reporter assays to prioritize causal variants from past GWAS, linking them to new and known target genes.
Alzheimer's Disease Risk Linked to New Loci in X Chromosome-Wide Association Study
Researchers found Alzheimer's disease risk loci on the X chromosome and focused in on a gene suspected to affect amyloid beta accumulation.
Postpartum Hemorrhage-Linked Loci Identified in Large GWAS, Meta-Analysis
Data for nearly 331,800 women from northern European cohorts helped researchers flag five postpartum hemorrhage-associated loci for subsequent functional analyses.
Gene Expression, Underlying Genetic Variation Profiled in Diverse Human Populations
Researchers generated RNA-seq data for 731 participants from the 1000 Genomes Project, digging into related gene regulation features across populations.