gene regulation Consortium Catalogs Variants Affecting Blood Gene Expression Members of the eQTLGen Consortium turned to data for almost 31,700 individuals to define local and distant expression quantitative trait loci affecting gene expression in the blood. Fast-Evolving Human Genome Sequences Found to Have Brain-Related Regulatory Roles An integrated analysis that spanned thousands of human accelerated regions suggested they harbor regulatory elements with roles in human brain development. Genome Biology Papers on Death Camp Forensics, Cancer Co-Regulation, Single-Cell Splice Junctions In Genome Biology this week: genetic evidence finds death camp remains belonged to members of Ashkenazi Jewish population, gene co-regulation of chromatin in cancer, and more. Type 1 Diabetes GWAS, Fine-Mapping Leads to New Genetic Loci, Potential Drug Targets Starting with a large GWAS, researchers incorporated chromatin accessibility data and other clues to find key variants, immune cell types, and treatment targets. Blood Cancer Genetic Risk Loci Found in Retriever Dogs Using a genome-wide association study and multiomic follow up, investigators tracked down genes involved in histiocytic sarcoma in flat-coated retrievers. Apr 21, 2021 Red Blood Cell Traits Linked to New Loci With Whole-Genome Sequencing Data Apr 15, 2021 At ACMG, Mechanism for Common Breast Cancer Locus Proposed From Functional Analysis Mar 4, 2021 Induced Pluripotent Stem Cells Show Potential for Finding New Regulatory Variants Feb 24, 2021 Proteogenomic Study Expands Catalog of Cell Cycle Players Feb 3, 2021 Human Epigenome Map Reveals New Insights Into Genetic Loci for Traits, Diseases Jan 5, 2021 Single-Cell Sequencing Reveals Immune Contributors to Exacerbated Asthma in Mouse Model Dec 11, 2020 COVID-19 GWAS Leads to Immune Genes Linked to Severe Disease, Treatment Targets Dec 8, 2020 Single-Cell Transcriptome Study Links Gut Development, Pediatric Crohn's Disease Dec 7, 2020 Neuroblastoma Super Enhancer Profiles Pinpoint Four Epigenetic Subtypes Oct 14, 2020 Epigenomic Study of Brain Development Uncovers Cell Type-Specific Regulatory Programs Sep 10, 2020 Longitudinal Irritable Bowel Syndrome Omics Study Points to Possible Treatment Target Jul 20, 2020 Prostate Cancer Metastasis Linked to Development-Related Epigenetic Shift Jul 13, 2020 Metastatic Prostate Cancer Methylation Analysis Reveals Subtype, Ties to Driver Genes Jul 9, 2020 Integrated Proteomic Papers Define Lung Cancer Features Across Populations, Smoking Histories Jun 23, 2020 Tissue Network Analysis Points to Significant Sex-Related Regulatory Differences Jun 9, 2020 Glioblastoma Genomes Point to Non-Coding Driver Mutations May 7, 2020 Primary Immunodeficiency Study Highlights Monogenic, Common Variant Disease Contributors Apr 16, 2020 Human Tumor Atlas Network Team Shares Strategy for Tracking Tumor Transitions Mar 9, 2020 Integrated Genomic Analysis Highlights Potential Strategy for Overcoming Some ALL Resistance Feb 14, 2020 Genetic Study of Snoring Highlights Ties to Diverse Traits, Behaviors Load More Breaking News Beckman Coulter, Invitae Partner to Develop NGS Library Prep Applications Sick Infants Profiled with WGS See Better Diagnosis, More Care Changes UC Santa Cruz Center for Live Cell Genomics Wins $13.5M NIH Grant Genetron Health, Impact Therapeutics Partner for Anti-Cancer Drug, CDx Development Canaccord Genuity Initiates Coverage of Pacific Biosciences With Buy Rating Alternative Genetic Counseling Approach Leads to Higher Patient Satisfaction, Study Suggests The Scan Highly Similar Researchers have uncovered bat viruses that are highly similar to SARS-CoV-2, according to Nature News. Gain of Oversight According to the Wall Street Journal, the Biden Administration is considering greater oversight of gain-of-function research. Lasker for mRNA Vaccine Work The Scientist reports that researchers whose work enabled the development of mRNA-based vaccines are among this year's Lasker Award winners PLOS Papers on Causal Variant Mapping, Ancient Salmonella, ALK Fusion Test for NSCLC In PLOS this week: MsCAVIAR approach to map causal variants, analysis of ancient Salmonella, and more.