Members of the International Human Epigenome Consortium published several new studies describing advances in understanding immune system regulation.
Using brain samples from individuals with or without autism spectrum disorder, researchers identified H3K27ac histone acetylation marks associated with ASD.
In Nature this week: genome of a Korean individual, genomic study of ancient settlers of Vanuatu and Tonga, and more.
In Nucleic Acids Research this week: transcriptome patterns of Zika-infected cells, updated Comparative Toxicogenomics Database, and more.
By focusing on sequences that have diverged rapidly in humans, researchers identified regulatory sequences suspected of affecting neural processes.
Truncations to PD-L1's 3' untranslated region were detected in a variety of tumor types, apparently increasing expression of the gene and decreasing immune response to it.
JHU's Alexis Battle is using whole-genome sequencing and RNA-sequencing data to identify and study the functional effects of rare non-coding variants.
A Stanford team found that variants in conserved binding sites reflect individuals' medical histories.
The University Medical Center Utrecht researchers' epigenomic analysis of primate brains uncovered human-specific cis gene-regulatory changes.
The researchers demonstrated that blocking the functioning of certain genes expanded the lifespan of lab animals.
In Science this week: deletion of one microRNA allows pluripotent stem cells to form embryonic and non-embryonic lineages, and more.
Arizona is planning to sue Theranos for "deceptive acts" and misrepresentations of its "capabilities and operation."
If confirmed as Department of Health and Human Services Secretary, Tom Price says he will divest himself of certain holdings, according to Stat News.
Oliver Smithies, who won the Nobel Prize in 2007, has died, the New York Times reports.