gene regulation
Breast Cancer Regulatory Networks Revealed in Single-Cell Study
Using single-cell epigenetic and transcriptomic analyses, researchers untangled regulatory features found within and across breast cancer subtypes.
Major Depression Contributors Uncovered in Multi-Ancestry GWAS Meta-Analysis
Researchers identified almost 700 major depression-associated variants using genotyping profiles for around 5 million diverse participants with or without major depression.
Alzheimer's Disease Study Catalogs Noncoding RNAs, Transcriptional Modifications in Brain Samples
Researchers highlighted noncoding RNAs and posttranscriptional modifications across six brain regions in 1,460 postmortem samples from individuals with or without Alzheimer's.
Researchers narrowed in on dual-treatment targets using expression and regulatory programs found in glioblastoma cells in and around the tumor.
Neural Gene Ties, Psychiatric Disorder Clues Found Using Complex Structural Variant Detection Tool
With the help of a probabilistic, machine-learning approach called ARC-SV, researchers found and began characterizing the brain effects of complex structural variants.