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gene expression

In urothelial cancer, the presence of a gene signature stemming from stromal cells seemed to interfere with anti-PD-1 drug response in tumors with infiltrating T-cells.

Using proteomic and genetic approaches, researchers identified a histone mark called lysine benzoylation that appears to be enhanced by exposure to sodium benzoate.

While the '3G' study did not establish clinical utility, the researchers said it shows genomic profiling to guide gastric cancer treatment is feasible.

Researchers used brain expression data from mice with well-documented sleep traits to identify gene networks that overlap with those in human depression.

The technique features sequencing-by-ligation and error-correction strategies, and was used to simultaneously map more than 1,000 genes in mouse brain tissue.

The German Federal Joint Committee (G-BA) plans to decide on reimbursement of breast cancer biomarker tests in Q4.

The approach, published this week in Cell Reports, could be used more generally to discover disease genes in other cancer types. 

The researchers designed a transcriptome sequencing assay that identifies clinically relevant gene fusions in 541 genes.

The Tel Aviv University researchers still noted some gene expression differences between lung epithelial cells infected with flu and bystander cells.

In a new analysis of the trial, researchers concluded that women over the age of 50 with recurrence scores below 25 appear to see no added benefit from adjuvant chemo.

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Nearly 30,000 COVID-19 tests the UK sent to the US came back as void, according to the Telegraph.

Black principal investigators receive less favorable application scores when seeking US National Institutes of Health grants, the Chronicle of Higher Education reports.

New Scientist reports that both RNA and DNA may have been involved in the emergence of life on Earth.

In Nature this week: new Sperm-seq method enables crossover analysis, tumor-informed detection approach for minimal residual disease, and more.