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gene expression

Gencurix aims to achieve US FDA 510(k) clearance for its GenesWell BCT breast cancer prognostic test next year.

A comparison of single-cell RNA sequencing profiles from more than 1,000 fresh or frozen samples suggests cryopreservation does not alter general transcriptome patterns.

A small study of Spanish women suggests maternal obesity may influence the genes expressed in placental tissue.

An international team of researchers examined differential gene expression in blood samples from patients infected during the West African outbreak.

In individuals diagnosed with prostate cancer before the age of 45, researchers saw enhanced expression of immune- and inflammation-related genes.

The single-cell approach enabled them to identify gene expression in rare cell types, highlighting a previously unrecognized role for these cells in diabetes. 

Roughly one-fifth of adult cases of acute lymphoblastic leukemia are marked by Philadelphia chromosome-like expression. 

Merck is hoping NanoString's multiplex platform can support gene expression signatures that will better predict which patients will respond to checkpoint inhibitors like its Keytruda.

The consortium aims to profile up to 800 multiple myeloma patient samples using the Affymetrix platform with a goal of developing a list of predictive biomarkers.

In colon tissue samples from individuals with Crohn's disease, researchers discovered either colon- or ileum-like expression features.

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NPR says the explosion and fire earlier this week at a Russian lab that stores dangerous pathogens revives the question of whether such samples should be kept.

According to Wired, Nebula Genomics is providing a way for people to get their genomes sequenced anonymously.

A 26-year-old woman tells Cosmopolitan about learning her APOE status at a young age.

In Science journals this week: a functional genomic screen uncovers drug combination that increases KRAS inhibitor efficacy in aggressive lung cancer, and more.