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gene expression

Researchers from the Netherlands have uncovered a new gene expression signature linked to ovarian cancer survival that is providing hints about potential pathways of importance for the disease. But authors warn that using such signatures for guiding treatment may be a ways off.

Affy aims to target downstream genomic-analysis markets with the products gained through its acquisitions of Panomics and True Materials last year, roll out new genotyping assays on its GeneTitan array platform, and consolidate its manufacturing facilities.

The activities are part of Kreatech's makeover from a biotech specializing in FISH probes and labeling kits, to a molecular diagnostics company with expertise in oncology, hematology, and constitutional disorders.

Short Reads: Feb 3, 2009

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Broad Institute, Expression Analysis, Helicos BioSciences, University of Texas at Austin, Applied Biosystems, University of Georgia, ABRF, Genomatix, Illumina, Mondobiotech, 23andMe, Kapa Biosystems

New Products: Feb 3, 2009

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CLC Genomics Workbench 3.0, CAMERA 1.3.2.28

Genotyping Tech Guide

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Genome Technology Genotyping Tech Guide

A team of Ontario researchers has identified a six-gene signature that can help predict non-small cell lung cancer outcomes — and uncovered evidence that there may be thousands of alternative prognostic signatures for the disease.

Roche will use Response Genetics' technology to assess a HER2 expression test.

The Realm of Noncoding RNAs

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Small (and not-so-small) noncoding RNAs have thrown a spanner in the works of understanding genome function. We take a look at the major questions brought about by micro-RNA, Piwi-interacting RNA, and more.

A Whole New System

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Now in its ninth year, the experiment that was the Institute for Systems Biology has become an established research organization known for its focus on translational science.

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The US has sent its formal notice of withdrawal from the World Health Organization, according to the Wall Street Journal.

Science reports that a draft spending bill would increase the US National Institutes of Health budget by 13 percent.

The Harvard Crimson reports that Harvard and MIT are suing the Department of Homeland Security and ICE over the new international student visa policy.

In Nucleic Acids Research this week: algorithm to determine molecular sequence types and other microbial features, computational method to uncover R-loop structures, and more.