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gene expression

Researchers from the Netherlands have uncovered a new gene expression signature linked to ovarian cancer survival that is providing hints about potential pathways of importance for the disease. But authors warn that using such signatures for guiding treatment may be a ways off.

Affy aims to target downstream genomic-analysis markets with the products gained through its acquisitions of Panomics and True Materials last year, roll out new genotyping assays on its GeneTitan array platform, and consolidate its manufacturing facilities.

The activities are part of Kreatech's makeover from a biotech specializing in FISH probes and labeling kits, to a molecular diagnostics company with expertise in oncology, hematology, and constitutional disorders.

Short Reads: Feb 3, 2009

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Broad Institute, Expression Analysis, Helicos BioSciences, University of Texas at Austin, Applied Biosystems, University of Georgia, ABRF, Genomatix, Illumina, Mondobiotech, 23andMe, Kapa Biosystems

New Products: Feb 3, 2009

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CLC Genomics Workbench 3.0, CAMERA 1.3.2.28

Genotyping Tech Guide

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Genome Technology Genotyping Tech Guide

A team of Ontario researchers has identified a six-gene signature that can help predict non-small cell lung cancer outcomes — and uncovered evidence that there may be thousands of alternative prognostic signatures for the disease.

Roche will use Response Genetics' technology to assess a HER2 expression test.

The Realm of Noncoding RNAs

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Small (and not-so-small) noncoding RNAs have thrown a spanner in the works of understanding genome function. We take a look at the major questions brought about by micro-RNA, Piwi-interacting RNA, and more.

A Whole New System

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Now in its ninth year, the experiment that was the Institute for Systems Biology has become an established research organization known for its focus on translational science.

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Retraction Watch reports that a paper was pulled because it refers to a gene that doesn't exist in mice.

Researchers were able to generate fertilized northern white rhinoceros eggs, according to Mashable.

Former Orig3n employees raise concerns about its testing at Bloomberg Businessweek.

In PLOS this week: microRNA expression changes in hepatocellular carcinoma, real-time PCR-based approach for diagnosing schistosomiasis, and more.