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gene expression

New analytical approaches combine single-cell RNA-seq profiles with in situ gene expression markers to place sequenced cells in a spatial context.

A meta-analysis of blood expression data for more than 7,000 individuals highlighted 34 transcripts with blood pressure-associated expression patterns.

A team scrutinized use of the 21-gene recurrence assay with the help of data on more than 70,800 individuals diagnosed with breast cancer between 2005 and 2009.

Two research teams have shown that stromal cells produce an expression profile associated with poor-prognosis forms of colorectal cancer.

The proof-of-principle application suggests networks of microRNA, RNA, and other 'omics data can untangle drug response and more.

Researchers have developed a tool called RNA-Rocket to link RNA-seq and ChIP-seq software with data from pathogen-related sequence databases.

Transposons with binding sites for the progesterone receptor lent nearby genes the ability to be regulated by the hormone, providing a mechanism to evolve a new trait. 

The algorithm could help detect potential circular RNAs for scientists to validate, opening up the poorly characterized genomic products for further study. 

The study demonstrated that the company's DecisionDx-Melanoma assay better predicts the risk of metastasis in patients with localized disease than clinical staging alone.

The test, which indicates risk of heart transplant rejection, is now available to patients in 11 additional states.

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New research shows that scientists need to do a better job of including a wider diversity of African genomes in their analyses, STAT says.

A new paper in Science shows that men are still winning a large majority of the most sought-after NIH grants.

Nature Research and the Estée Lauder Companies are awarding efforts to encourage girls to pursue careers in the STEM fields.

In Science this week: beneficial genetic variants inherited from archaic Neanderthal and Denisovan hominins, and more.