The researchers demonstrated that blocking the functioning of certain genes expanded the lifespan of lab animals.
The approach uses a technique called Earth mover's distance borrowed from image processing to identify differentially expressed genes across a set of samples.
A five-gene signature was linked to both event-free survival and overall survival in individuals with a type of rhabdomyosarcoma missing a prognostically informative gene fusion.
Array-based gene expression data suggests luminal and basal subtypes present in both human and canine forms of invasive urothelial carcinoma.
Researchers have developed a gene expression signature of healthy aging that can identify people at risk of Alzheimer's disease.
PrediXcan combines gene expression-level information with trait data to predict which genes likely play a role in heritable diseases and observed phenotypes.
Using a method that relied on Affymetrix arrays, researchers found that 38 patients in the trial had gene expression indicating they were in the ABC subtype.
Researchers used RNA interference and automated trait analyses to systematically track phenotypes in Caenorhabditis elegans worms from two genetic backgrounds.
The company is developing a test to predict RA patients' response to various drugs beginning with anti-TNF therapy, which it highlighted in a recent publication.
In three studies, researchers present new evidence on how gene expression differs across different tissues, and how DNA variations influence and alter this expression.
Google's Project Nightingale has collected health information on millions of Americans, according to the Wall Street Journal.
An opinion piece at The Hill criticizes the proposed plan to collect DNA samples from migrants at the US border.
Nature News writes that women in chemistry are less likely to have their manuscripts accepted for publication.
In PNAS this week: tRNA fragment signature for chronic lymphocytic leukemia, genomic sites sensitive to ultraviolet radiation in melanocytes, and more.