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gene expression

Merck is hoping NanoString's multiplex platform can support gene expression signatures that will better predict which patients will respond to checkpoint inhibitors like its Keytruda.

The consortium aims to profile up to 800 multiple myeloma patient samples using the Affymetrix platform with a goal of developing a list of predictive biomarkers.

In colon tissue samples from individuals with Crohn's disease, researchers discovered either colon- or ileum-like expression features.

A study by researchers in Austria suggests read depth patterns upstream of transcription start sites can provide clues to gene expression.

The study found that combining whole-genome expression or genome-wide methylation data with clinical data improves survival predictions in breast cancer cases.

Transcriptional response of pro-inflammatory and antiviral genes in the face of childhood trauma is linked to PTSD but can be mitigated.

The European Commission recently awarded the researchers €1.5 million to probe the mechanics of heart failure using proteomic, genomic, and epidemiological approaches.

Physicians relied on MammaPrint to decide whether patients scoring in the middle range for cancer recurrence risk with Oncotype DX should receive chemotherapy.

VPR, SAM and SunTag all performed admirably in driving gene expression in a number of different human and model organism cell types.

Researchers identified genes with differential expression in blood from cattle with pre-clinical or clinical cases of atypical bovine spongiform encephalopathy.

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Rady Children's Institute for Genomic Medicine and Deloitte are looking into the use of drones to transport samples for testing. 

Direct-to-consumer genetic testing firm 23andMe is laying off about 100 people.

Researchers from Northwestern University examined dust for antibiotic-resistance genes, New Scientist reports. 

In Science this week: researchers present a computational method for predicting cellular differentiation state from single-cell RNA sequencing data, and more.