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gene expression

The company's two largest investors will purchase $25 million of its common shares, with proceeds supporting ongoing test commercialization.

Investigators identified five expression subtypes spanning three broader clusters in postmortem parahippocampal gyrus samples from Alzheimer's patients.

Investigators saw enhanced interleukin-13 production by a handful of immune cell types in mouse models of steroid-resistant asthma.

Researchers used single-cell RNA sequencing to delve into intra-tumoral heterogeneity in peritoneal carcinomatosis, identifying a potential prognostic signature.

FLEX will include full transcriptome data paired with 800 data points from 10,000 patients, offering researchers the chance to study diverse patient subsets.

Researchers identified several immune-related genes in a GWAS that included more than 2,200 COVID-19 patients treated in UK intensive care units.

Researchers saw transcription factor similarities between developing human intestinal cells and cells from pediatric Crohn's disease cases.

Using a combination of genomic and epigenomic profiling, researchers spelled out super enhancer-based subtypes, including one linked to poor clinical outcomes.

Within the KiCS study researchers found targetable mutations in more than half of the kids, but few actually received drugs based on those molecular markers.

The findings gave insight into how Plasmodium falciparum persists as a subclinical infection during the dry season, when there are no mosquitoes to transmit it.

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The Financial Times reports the US bolstering its ability to track SARS-CoV-2 alterations.

The New York Times reports that Cedars-Sinai researchers have uncovered a new strain of SARS-CoV-2 in Southern California.

In Nucleic Acids Research this week: pan-cancer atlas focus on miRNA biogenesis mutations, methylation analysis of pig skeletal muscles, and more.

President-elect Joe Biden has nominated Eric Lander to serve as director of the Office of Science and Technology Policy, the Associated Press says.