An international team of researchers examined differential gene expression in blood samples from patients infected during the West African outbreak.
In individuals diagnosed with prostate cancer before the age of 45, researchers saw enhanced expression of immune- and inflammation-related genes.
The single-cell approach enabled them to identify gene expression in rare cell types, highlighting a previously unrecognized role for these cells in diabetes.
Roughly one-fifth of adult cases of acute lymphoblastic leukemia are marked by Philadelphia chromosome-like expression.
Merck is hoping NanoString's multiplex platform can support gene expression signatures that will better predict which patients will respond to checkpoint inhibitors like its Keytruda.
The consortium aims to profile up to 800 multiple myeloma patient samples using the Affymetrix platform with a goal of developing a list of predictive biomarkers.
In colon tissue samples from individuals with Crohn's disease, researchers discovered either colon- or ileum-like expression features.
A study by researchers in Austria suggests read depth patterns upstream of transcription start sites can provide clues to gene expression.
The study found that combining whole-genome expression or genome-wide methylation data with clinical data improves survival predictions in breast cancer cases.
Transcriptional response of pro-inflammatory and antiviral genes in the face of childhood trauma is linked to PTSD but can be mitigated.
In Science this week: metagenomic-based technique for determining protein structure, and more.
An academic laments the rise of narcissism in the sciences, the Guardian reports.
Outgoing FDA commissioner Robert Califf writes in an editorial that the agency can help boost innovation.
The Trump transition team has asked NIH Director Francis Collins to remain at his post, though it's unclear for how long that will be.