gene expression | GenomeWeb

gene expression

A comparison of single-cell RNA sequencing profiles from more than 1,000 fresh or frozen samples suggests cryopreservation does not alter general transcriptome patterns.

A small study of Spanish women suggests maternal obesity may influence the genes expressed in placental tissue.

An international team of researchers examined differential gene expression in blood samples from patients infected during the West African outbreak.

In individuals diagnosed with prostate cancer before the age of 45, researchers saw enhanced expression of immune- and inflammation-related genes.

The single-cell approach enabled them to identify gene expression in rare cell types, highlighting a previously unrecognized role for these cells in diabetes. 

Roughly one-fifth of adult cases of acute lymphoblastic leukemia are marked by Philadelphia chromosome-like expression. 

Merck is hoping NanoString's multiplex platform can support gene expression signatures that will better predict which patients will respond to checkpoint inhibitors like its Keytruda.

The consortium aims to profile up to 800 multiple myeloma patient samples using the Affymetrix platform with a goal of developing a list of predictive biomarkers.

In colon tissue samples from individuals with Crohn's disease, researchers discovered either colon- or ileum-like expression features.

A study by researchers in Austria suggests read depth patterns upstream of transcription start sites can provide clues to gene expression.

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An opinion piece in the New York Times urges lawmakers to keep genetic protections in place.

Research funding in Canada is to remain mostly the same, ScienceInsider reports.

In Science this week: random DNA replication errors play role in cancer, and more.

The Bill and Melinda Gates Foundation embarks on an open-access publishing path.