GC-rich
The assay was shown to have a simpler workflow and was able to detect mosaicism, with only a slight decrease in sensitivity compared to a lab-developed test.
Cas1-Cas2 Integrase Structures Enable Bacteria to Adapt to New Viruses
Researchers led by Jennifer Doudna found that the architecture of the Cas1-Cas2 integrase contributes to bacterial adaptive immunity.
Scientists from the institute developed a panel of qPCR assays to identify the primary causes of PCR amplification bias in Illumina sequencing libraries, and optimized a protocol that can help reduce such bias.