FLT3 Japanese Regulators Approve Invivoscribe Assay as CDx for Daiichi Sankyo AML Drug The LeukoStrat CDx FLT3 Mutation Assay can now be used in Japan as the CDx for quizartinib for the treatment of FLT3-ITD positive relapsed or refractory AML. Single-Cell Sequencing Proves Useful for Tracking Drug-Resistant AML Mutation Progression Premium Researchers used Mission Bio's Tapestri assay to identify and monitor the evolution of cancer mutations in acute myeloid leukemia in response to targeted treatment. FLT3 Inhibitor Treatment Improves Survival in Relapsed, Refractory AML Patients With Mutations Results from the phase 3 ADMIRAL trial were announced during the American Association for Cancer Research annual meeting. First Veterans Affairs MDx Lab Launches NGS-Based Cancer Panel; Others to Follow Premium The VA decided to bring this testing in house to streamline and standardize the process for doctors and gauge markers that are relevant to the veteran population. Invivoscribe CDx Assay Gets Expanded FDA Approval Alongside Astellas AML Drug The LeukoStrat CDx FLT3 Mutation Assay is a PCR-based test for internal tandem duplications and tyrosine kinase domain mutations D835 and I836 in the FLT3 gene. Nov 27, 2018 Invivoscribe Submits FLT3 Mutation CDx Assay to FDA Nov 19, 2018 Invivoscribe Submits FLT3 Mutation Assay CDx to Japanese Regulators Sep 27, 2018 Invivoscribe Receives Regulatory Approval for FLT3 Mutation Assay in Japan Jun 26, 2018 Rare Immune Cells, Cytokine May Predict Response to Cancer Immunotherapy May 8, 2018 Invivoscribe Submits Regulatory Applications in Japan, US for AML CDx Feb 6, 2018 Sophia Genetics Gains CE-IVD Mark for Leukemia Assay Aug 1, 2017 Invivoscribe Garners CE Mark for LeukoStrat CDx FLT3 Mutation Assay Apr 28, 2017 FDA Approves Rx/Dx Combination for Acute Myeloid Leukemia Jan 31, 2017 Invivoscribe, Thermo Fisher to Develop FLT3 Mutation, Clonality Assay Kits Mar 20, 2015 Genection's AML Panel First of Several NGS-based Dx Tests it Plans to Bring Through FDA Clearance Premium Nov 19, 2014 Dana-Farber, Brigham and Women's Develop NGS Panel for Rapid Diagnosis of Hematologic Cancers Premium Dec 14, 2011 Plexxikon Launching Phase I/II Trial for PLX3397 in AML Patients with Flt3 Mutations Premium Feb 23, 2011 Novartis, Invivoscribe to Develop Companion Test for Acute Myeloid Leukemia Rx Midostaurin Premium Breaking News FDA Warns of Potential False Positives With Abbott SARS-CoV-2 Molecular Tests New Products Posted to GenomeWeb: Oxford Nanopore, Beckman Coulter, Thermo Fisher Scientific, More People in the News: New Appointments at Sema4, NHGRI, Dante Labs, Ancestry, More Thermo Fisher Scientific Expects 12 Percent Revenue Growth in 2022 In Brief This Week: Myriad Genetics, Danaher, Co-Diagnostics, and More Vibrent Health, University of Maryland Medicine Partner for Population Health Initiative The Scan For Those Thick Tiger Stripes Tigers in India with thick stripes harbor a genetic change, as Gizmodo reports. High GABA Tomatoes The Japan News reports that genome-edited tomatoes with higher GABA levels are now for sale in Japan. Approach for Inclusivity and Diversity A National Human Genome Research Institute team calls for the field to "adopt diversity as an ethos." Science Papers on Tumors Immune System Evasion; Drivers of Genomic Instability, Inflammation In Science this week: study of how tumors evade the adaptive immune system, and more.