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evolutionary biology

Using haplotype profiling, phylogenetics, and other analyses, researchers retraced sickle allele emergence to a single event occurring roughly 7,300 years ago.

Researchers discovered thousands of candidate functional elements by searching diverse mammalian genomes for regions of accelerated evolution within highly conserved sites.

Research on phages in CRISPR-Cas9-containing Escherichia coli indicated that pressure exerted by the bacterial defense system can boost phage mutation frequency.

In PLOS this week: ramifications of sexual recombination in bacteria, Mycobacterium leprae genome sequences, and more.

Still Evolving

A new paper in PNAS finds that people are still evolving, but with increased pressure on weight and decreased pressure on intelligence.

Tasmanian tiger/thylacine/Tasmanian wolf

A genomic analysis of the Tasmanian tiger pointed to early genetic diversity declines in the species, while offering clues to convergent canid features.

In Cell this week: integrated genomic analysis of adult soft tissue sarcoma, positive selection has greater role in cancer than negative selection, and more.

In PNAS this week: effector proteins contributing to Legionnaires' disease virulence, proteomic analysis of transition to quiescence, and more.

Batang Toru orangutan

Using genome sequencing, phylogenomics, morphological analyses, and more, investigators defined a rare new orangutan species dubbed Pongo tapanuliensis.

University of Chicago researchers combined epidemiological and viral gene evolution data to refine influenza modeling.

Pages

Holden Thorp is to be the new editor-in-chief of Science and its related journals.

A genetic analysis of salmon scales collected over the course of a century points to a sharp decline in the number of fish returning each year to river in British Columbia, CBC reports.

Adelaide University has suspended the head of an ancient DNA lab as its investigation of workplace bullying continues, Australia's ABC News reports.

In PNAS this week: gene expression profiles of adipocyte subtypes, computational approach for improving plant expressome analysis, and more.