Using haplotype profiling, phylogenetics, and other analyses, researchers retraced sickle allele emergence to a single event occurring roughly 7,300 years ago.
Researchers discovered thousands of candidate functional elements by searching diverse mammalian genomes for regions of accelerated evolution within highly conserved sites.
Research on phages in CRISPR-Cas9-containing Escherichia coli indicated that pressure exerted by the bacterial defense system can boost phage mutation frequency.
In PLOS this week: ramifications of sexual recombination in bacteria, Mycobacterium leprae genome sequences, and more.
A new paper in PNAS finds that people are still evolving, but with increased pressure on weight and decreased pressure on intelligence.
A genomic analysis of the Tasmanian tiger pointed to early genetic diversity declines in the species, while offering clues to convergent canid features.
In Cell this week: integrated genomic analysis of adult soft tissue sarcoma, positive selection has greater role in cancer than negative selection, and more.
In PNAS this week: effector proteins contributing to Legionnaires' disease virulence, proteomic analysis of transition to quiescence, and more.
Using genome sequencing, phylogenomics, morphological analyses, and more, investigators defined a rare new orangutan species dubbed Pongo tapanuliensis.
University of Chicago researchers combined epidemiological and viral gene evolution data to refine influenza modeling.
A South African university has told the Wellcome Sanger Institute to return DNA samples it has from indigenous African communities, The Times reports.
The University of California, Berkeley's Rasmus Nielsen and Xinzhu Wei have retracted their CCR5 gene paper due to a technical artifact.
University of Virginia researchers are exploring a genetic risk test to gauge type 1 diabetes risk, NPR reports.
In PNAS this week: researchers compare two high-grade neuroendocrine lung cancers, height among ancient Europeans, and more.