The system, called EvolvR, can continuously diversify all nucleotides within a tunable window at user-defined loci using CRISPR-guided nickases.
Using genome sequencing and phylogenetics, researchers have shown that the industrial yeast Pichia kudriavzevii is genetically the same species as Candida krusei.
From infant skeletal remains going back hundreds of years, a team produced three Treponema pallidum genomes, representing both syphilis- and yaws-causing sub-species.
In PLOS this week: comparison of commercial bisulfite kits, new method to predict essential proteins, and more
Researchers have uncovered a trio of human-specific genes that seem to govern people's large brain size, Reuters reports.
Using bioinformatic and molecular cytogenetic approaches, researchers retraced ancestral "diapsid" reptile genome patterns from extant bird and reptile genomes.
Sequencing the genomes of a half a dozen chimp- or gorilla-infecting malaria parasites provided a clearer picture of Plasmodium falciparum evolution.
A phylogenetic analysis of green-blooded lizards find the trait likely arose more than once, Reuters reports.
An analysis of more than 1,000 Neisseria gonorrhoeae genomes provided insights into antibiotic resistance patterns and related genomic features.
A multi-region analysis of colorectal cancers suggests samples from opposite sides of a tumor can help trace early, invasiveness-related tumor characteristics.
NPR reports that the patient who underwent a CRISPR-based treatment for sickle cell disease is doing well.
Resistance to ash dieback disease among some UK ash trees appears polygenic, the Independent reports.
In Nucleic Acids Research this week: sequencing strategy for flash-frozen brain tissue bank samples, new version of ChlamDB, and more.
A UK woman is suing three National Health Service Trusts for not telling her about her father's Huntington's disease diagnosis, the BBC reports.