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evolutionary biology

This Week in PLOS

In PLOS this week: comparison of commercial bisulfite kits, new method to predict essential proteins, and more

Got Big Brains

Researchers have uncovered a trio of human-specific genes that seem to govern people's large brain size, Reuters reports.

Velociraptor mongoliensis

Using bioinformatic and molecular cytogenetic approaches, researchers retraced ancestral "diapsid" reptile genome patterns from extant bird and reptile genomes.

Sequencing the genomes of a half a dozen chimp- or gorilla-infecting malaria parasites provided a clearer picture of Plasmodium falciparum evolution.

And Aren't Vulcan

A phylogenetic analysis of green-blooded lizards find the trait likely arose more than once, Reuters reports.

An analysis of more than 1,000 Neisseria gonorrhoeae genomes provided insights into antibiotic resistance patterns and related genomic features.

A multi-region analysis of colorectal cancers suggests samples from opposite sides of a tumor can help trace early, invasiveness-related tumor characteristics.

With genome-wide association study data, researchers saw enrichment for schizophrenia-linked SNPs in human-specific differentially methylated regions.

Dramatic genetic diversity in Mycobacterium leprae isolates from medieval Europe could point to a long history or potential origins on the continent.

Independent research teams identified and sequenced hepatitis B strains going back thousands of years from samples in Europe, uncovering now-extinct lineages.

Pages

Researchers tie a variant in ADAMTS3 to breathing difficulties in dissimilar dog breeds, according to Discover's D-brief blog.

The Japan Times reports that researchers sequenced the genome of a woman who lived during the Jomon period.

Parents of children with rare genetic disease have to contend with shifts in the interpretation of genetic variants, the Wall Street Journal reports.

In Science this week: single-nucleus RNA sequencing of brain tissue from individuals with autism, and more.