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evolutionary biology

In PNAS this week: copy number changes arose during polar bear evolution, genomic and transcriptomic analysis of the Siberian hamster, and more.

This Week in PNAS

In PNAS this week: tool to predict pathogenic gene pairs, analysis of bat evolution, and more.

Based on sequences for hundreds of E. coli ST131 lineage isolates, researchers propose a model that involves negative frequency-dependent selection on accessory parts of the genome.

To understand the evolution of brain conditions and other traits, investigators plan to sequence human and pathogen DNA in thousands of samples from Europe.

Using genome sequences for 161 present-day Papuans and Island Southeast Asians, researchers described three Denisovan lineages and estimated divergence times between them.

This Week in Science

In Science this week: genomic study of convergent evolution of the loss of flight in birds, and more.

Molecular features in primary and recurrent glioblastomas indicated that key initiator mutations turned up years before diagnosis, often persisting in recurrent tumors.

With RNA sequencing and other data, researchers gauged neoantigen formation, immunoediting, and clonal evolution in non-small cell lung cancers.

This Week in Science

In Science this week: mechanisms of trait adaptation in wild mice, and more.

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Science reports on a preprint that looks into horizontal gene transfer events between eukaryotes and prokaryotes.

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Three genetic testing companies form a coalition to influence how Congress considers genetic privacy, The Hill reports.

University of California, San Diego researchers investigate how skin care products influence the skin microbiome, Scientific American reports.

The Wall Street Journal examines billing codes used by uBiome.

In PNAS this week: links between lung adenocarcinoma and lncRNA, algorithm to impute and cluster Hi-C interaction profiles from single cells, and more.