To understand the evolution of brain conditions and other traits, investigators plan to sequence human and pathogen DNA in thousands of samples from Europe.
Using genome sequences for 161 present-day Papuans and Island Southeast Asians, researchers described three Denisovan lineages and estimated divergence times between them.
Molecular features in primary and recurrent glioblastomas indicated that key initiator mutations turned up years before diagnosis, often persisting in recurrent tumors.
The researchers generated a skull shape score and applied it to a European ancestry cohort to tease out introgressed Neanderthal DNA linked to head shape.
St. Jude Children's Research Hospital scientists have treated infants with X-linked severe combined immunodeficiency using gene therapy in an early phase study.
In Nature this week: a genomic analysis of the snailfish Pseudoliparis swirei, ancient DNA analysis gives insight into the introduction of farming to England, and more.
