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One of the ancient mammoths sequenced belongs to a previously unknown lineage that hybridized with woolly mammoths to give rise to Columbian mammoths.
Researchers used CRISPR to reintroduce an archaic variant of NOVA1 into cortical organoids to study how a human-specific variant may have affected evolution.
The researchers, who also performed whole-genome sequencing on 853 macaques, found new lineage-specific genes and expanded gene families in the monkeys.
The Zoonomia Project and the Bird 10,000 Genomes Project have reported new genome sequences that could inform conservation and other efforts.
Data presented at the ASHG virtual meeting highlighted the population insights that can be gleaned from IDB profiles in populations, including loci linked to blood traits.
Sequencing of ancient samples showed that Denisovan Y chromosomes split around 700,000 years ago from a lineage shared by Neanderthals and modern humans.
Ebola viruses passaged in bat renal cells appeared to be subject to RNA editing by host enzymes, while more adaptive mutations arose after passaging in a human kidney cell line.
With a new analytical tool, researchers uncovered ancient archaic hominin sequences in the Denisovan genome, along with human introgression into Neanderthals up to 300,000 years ago.
With genome sequence alignments and phylogenetic analyses focused on non-recombining regions, researchers traced the SARS-CoV-2 lineage in bats back at least 40 years.
Ancestral alleles "reintroduced" by Neanderthal admixture are prone to functional in the human genome, based on an analysis of East Asian, South Asian, and European sequences.
Politico reports that the NYPD DNA database has grown since it announced it would be removing profiles from it.
Forbes reports that a structural biology lab at Oxford University studying the coronavirus was hacked.
Science reports that a Dutch research funding agency is combating a ransomware attack.
In Science this week: set of 64 haplotype assemblies from 32 individuals, and more.