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evolutionary biology

To understand the evolution of brain conditions and other traits, investigators plan to sequence human and pathogen DNA in thousands of samples from Europe.

Using genome sequences for 161 present-day Papuans and Island Southeast Asians, researchers described three Denisovan lineages and estimated divergence times between them.

This Week in Science

In Science this week: genomic study of convergent evolution of the loss of flight in birds, and more.

Molecular features in primary and recurrent glioblastomas indicated that key initiator mutations turned up years before diagnosis, often persisting in recurrent tumors.

With RNA sequencing and other data, researchers gauged neoantigen formation, immunoediting, and clonal evolution in non-small cell lung cancers.

This Week in Science

In Science this week: mechanisms of trait adaptation in wild mice, and more.

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Science reports on a preprint that looks into horizontal gene transfer events between eukaryotes and prokaryotes.

Researchers also found that Neanderthals differed from humans more in the regulatory than protein-coding sequences of their genomes.

The researchers generated a skull shape score and applied it to a European ancestry cohort to tease out introgressed Neanderthal DNA linked to head shape.

This Week in Nature

In Nature this week: full UK Biobank dataset published, shark genomes give glimpse into cartilaginous fish evolution, and more.

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The long-running Framingham Heart Study has received a $38 million grant, according to the Boston Globe.

A Stanford University investigation finds that its researchers did not take part in He Jiankui's work to develop gene-edited infants.

Retraction Watch reports that two researchers had both a Science and a Nature paper retracted last week.

In Genome Biology this week: genomic sequencing of milkweed bug, benchmark comparison of single-cell RNA sequencing platforms, and more.