ER/PgR Mutations in FOXA1 Gene Can Affect Breast Cancer Patients' Response to Therapy A new study found that FOXA1 missense mutations were enriched in metastatic breast tumors and New Data Support Role of Agendia BluePrint Test in Refining Breast Cancer Subtypes Premium At the American Society of Clinical Oncology's virtual meeting, investigators presented two new studies of BluePrint classification patterns. OncotypeDX Score May Give Valuable Info on Breast Cancer Locoregional Recurrence Such prognostic information could aid clinicians in making decisions about radiotherapy for postmenopausal women with breast cancer. Researchers Identify Breast Cancer Target Genes Via Fine-Mapping of Disease Risk Regions The investigators used gene expression, chromatin interaction, and functional annotations to prioritize 191 genes as targets of potentially causal variants. ER-Positive Breast Cancer Outcomes Linked to New, Known Somatic Mutations With targeted gene sequencing data from a large set of archived tumor samples, researchers identified somatic mutations coinciding with better or worse overall survival. Apr 21, 2010 CAP/ASCO Issues New Guidelines to Improve IHC-based ER/PgR Analysis in Breast Cancer Premium Breaking News Genetic Loci With Link to Bowel Movement Frequency May Point to GI Condition Treatments Rebus Biosystems Acquires IP, Assay Assets of EEL Transcriptomics Genedrive Rapid Molecular COVID-19 Test Receives CE Mark Nomic Bio Closes $17M Series A Round Pacific Biosciences, UCLA Collaborate on Rare Disease Diagnostics Foundation Medicine Test Nabs FDA Approval as CDx for BRAF Inhibitor Therapeutics for Melanoma The Scan Back as Director A court has reinstated Nicole Boivin as director of the Max Planck Institute for the Science of Human History, Science reports. Research, But Implementation? Francis Collins reflects on his years as the director of the US National Institutes of Health with NPR. For the False Negatives The Guardian writes that the UK Health Security Agency is considering legal action against the lab that reported thousands of false negative COVID-19 test results. Genome Biology Papers Present Epigenetics Benchmarking Resource, Genomic Architecture Maps of Peanuts, More In Genome Biology this week: DNA methylation data for seven reference cell lines, three-dimensional genome architecture maps of peanut lines, and more.