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EGFR Biomarkers

News and reporting on EGFR biomarkers.

The scientific organizations are revisiting the topic of molecular testing for lung cancer patients just a year and a half after releasing the initial guidelines. 

The company, whose technology enables the selective amplification of mutant DNA, will use the financing to ramp up its commercialization work and build its product portfolio.

The collaboration will explore the clinical utility of Trovagene's platform for detecting and monitoring EGFR mutations in lung cancer patients. 

A study comparing DNA extracted from standardized blocks of FFPE showed variability among experienced molecular pathology labs.

New survival data suggest that patients with del19 mutations should receive Gilotrif as their top option and that researchers should no longer clump different EGFR-mutated subpopulations together in research, lead study investigator Lecia Sequist said.

Originally published Sept. 25.
NEW YORK (GenomeWeb) – The National Cancer Institute this week kicked off its exceptional responders program, in which researchers will sequence tumor tissue from patients who have had an outlier response to investigational treatments.

NEW YORK (GenomeWeb) – The recent lawsuit filed by Esoterix Genetic Laboratories against Qiagen over an alleged breached licensing agreement covering EGFR testing may be a message to other labs who have sold tests without a license.

NEW YORK (GenomeWeb) — Researchers from several European institutions working with AstraZeneca have published a study demonstrating that measuring EGFR mutations from circulating tumor DNA compares favorably to tissue-based EGFR mutation status.

NEW YORK (GenomeWeb) – LabCorp subsidiary Esoterix Genetic Laboratories is suing Qiagen in a US district court alleging that Qiagen breached a licensing agreement between the companies regarding EGFR genetic testing by offering it for commercial research and diagnostic purposes ahead of US Food a

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Anthony Fauci also informed the World Health Organization executive board that the US would be joining the COVAX initiative, according to CNBC.

Politico notes that the Biden Administration has not yet nominated a permanent Food and Drug Administration commissioner. 

A new preprint suggests some SARS-CoV-2 variants could affect the effectiveness of current vaccines, the Associated Press reports.

In Nature this week: Australian lungfish provides details on the movement of vertebrate life from water to land, and more.