EGFR inhibitors FDA Approves Janssen's Rybrevant, Guardant360 CDx for EGFR Exon 20-Mutated NSCLC The agency approved amivantamab for non-small cell lung cancer patients harboring EGFR exon 20 mutations, as detected by Guardant Health's blood-based test. Comparison of KRAS Liquid Biopsy Kits Confirms Differences at Low Mutant Allele Fraction Biocartis' Idylla called some colorectal cancer samples negative that Sysmex Inostics's OncoBEAM called positive, but the clinical implications may be complex. Sysmex Gets Japanese Manufacturing, Marketing Approval for Colorectal Cancer Screening Assay The firm believes that physicians can use information from the cell-free DNA analyzed by the assay to determine whether to use anti-EGFR drugs during treatment. China's NMPA Extends Approval for Roche Cobas EGFR Mutation Test v2 to Plasma Samples Labs in China can now use the Cobas EGFR Mutation Test v2 with either tissue or plasma samples as a CDx for three Roche oncology drugs in NSCLC patients. Colon Cancer Patients Could Benefit From HER2 EGFR Non-Response Findings, Investigators Say Premium Based on the findings, MD Anderson is already using HER2 status to recommend patients for clinical trials instead of EGFR drugs and authors recommend others follow suit. Jun 6, 2017 New Precision Oncology Options Emerge at ASCO in First-Line EGFR-Mutated, ALK-Positive Lung Cancer Premium Mar 14, 2017 Roche EGFR Mutation Test Approved in Canada Apr 15, 2016 Expansion of Liquid Biopsy Test Sites Planned by Merck KGaA, Sysmex Premium Apr 7, 2016 Merck KGaA, Sysmex Inostics Garner CE Mark for Liquid Biopsy CRC Test Apr 4, 2016 Researchers Develop Whole-Exome Sequencing Pipeline to ID Variants, Match Patients to Drugs Premium Jan 29, 2016 AstraZeneca Shows Off Quick Uptake of CRISPR Tech in Drug Discovery Process Premium Sep 28, 2015 Roche's Cobas EGFR Assay Gets CE Mark Jul 14, 2015 Iressa Approval Grows Options for Lung Cancer Patients as AstraZeneca Re-establishes Presence Premium Jul 13, 2015 FDA Approves Qiagen's Therascreen EGFR Test as CDx for AstraZeneca NSCLC Drug Jun 4, 2015 Italian Team Uses Liquid Biopsy to Show Dynamic Nature of Tumor Response to Therapy Premium Mar 30, 2015 CAP, AMP Among Groups Jointly Issuing Colorectal Cancer Molecular Testing Draft Recommendations Mar 4, 2015 Study Shows cfDNA EGFR Mutations Linked to Tarceva Outcome in EURTAC Samples Premium Feb 18, 2015 Clovis Evaluating Sysmex Inostics Blood Assay to ID EGFR Mutations in ctDNA of NSCLC Patients Premium Dec 16, 2014 IntegraGen, PICCOLO Researchers Collaborate to Validate Metastatic Colorectal Cancer Biomarker Sep 3, 2014 EGL Lawsuit against Qiagen Could Be Warning to Labs Performing EGFR Testing Without License Premium Aug 27, 2014 Circulating DNA an Appropriate Alternative for EGFR Testing When Tissue Unavailable, Study Finds Premium Jun 18, 2014 Georgetown Team Planning Human Trial after Finding Targetable Marker of EGFR Inhibitor Resistance Premium Dec 5, 2013 Brain Tumors Evade Tailored Therapies by Eliminating Targeted Mutation May 15, 2013 Transgenomic to Develop RAS Mutation Test with Amgen for Metastatic CRC Patients Premium Aug 17, 2011 Pfizer Using Qiagen KRAS Test to Study Dacomitinib Head-to-Head Against Tarceva in NSCLC Premium Load More Breaking News Children With Autism May Have Underdeveloped Gut Microbiomes, Metagenomic Analysis Finds Kiromic BioPharma Acquires InSilico Solutions Bio-Rad Laboratories, 10x Genomics Settle IP Lawsuits, Sign Global Cross-Licensing Agreement Scope Fluidics Obtains CE Mark for PCR-Based SARS-CoV-2 Panel MeMed COVID-19 Prognostic Test Receives CE Mark ERS Genomics Licenses CRISPR IP to Japan SLC The Scan Dropped Charges The US Justice Department has dropped visa fraud charges against five Chinese researchers, according to the Wall Street Journal. More Kids The Associated Press says Moderna is expanding its SARS-CoV-2 vaccine study to included additional children and may include even younger children. PNAS Papers on Rat Clues to Human Migration, Thyroid Cancer, PolyG-DS In PNAS this week: ancient rat genome analysis gives hints to human migrations, WDR77 gene mutations in thyroid cancer, and more. Purnell Choppin Dies Purnell Choppin, a virologist who led the Howard Hughes Medical Institute, has died at 91, according to the Washington Post.