EGFR Biomarkers News and reporting on EGFR biomarkers. Molecular Clonal Tracking Method Captures Lung Cancer Treatment Response, Resistance Features Using a single-cell sequencing and clonal fitness mapping method, researchers compared EGFR-mutant lung cancer cell responses to EGFR inhibition or targeted protein degradation. FDA Approves Takeda's Exkivity With Thermo Fisher CDx for EGFR Exon20 Insertion-Positive NSCLC This is the first time the FDA has approved a drug specifically for NSCLC patients who harbor rare EGFR Exon20 insertion mutations. Genecast to Evaluate Liquid Biopsy EGFR Mutation Test in Early-Stage Non-Small Cell Lung Cancer The firm hopes its qPCR-based liquid biopsy test could help identify early-stage NSCLC patients eligible for adjuvant or neoadjuvant anti-EGFR TKI treatment. Liquid Biopsy-Guided EGFR Rechallenge Therapy Shows Benefit for Colorectal Cancer Patients The first interventional trial to use ctDNA to recruit eligible patients for this treatment showed 30 percent observable responses and more than 60 percent disease control. FDA Approves Janssen's Rybrevant, Guardant360 CDx for EGFR Exon 20-Mutated NSCLC The agency approved amivantamab for non-small cell lung cancer patients harboring EGFR exon 20 mutations, as detected by Guardant Health's blood-based test. Feb 23, 2021 Biocept, Protean BioDiagnostics Team up to Study EGFR Assay in Lung Cancer Oct 29, 2020 Roche EGFR Mutation Test Approved by FDA as Companion Diagnostic for NSCLC Jul 8, 2020 Guardant Health to Develop Liquid Biopsy Companion Diagnostic for Janssen NSCLC Therapy Jun 17, 2020 Stilla Positions Six-Color Digital PCR System for Use in Oncology, Virology, GMO Testing Premium Apr 27, 2020 Amid COVID-19, Lower Cancer Diagnosis Rates Mean Fewer Patients Getting Molecular Tests, Treatment Premium Apr 19, 2020 Despite FDA Guidance, CDx Providers Still Have Challenges in Seeking 'Therapeutic Group' Indication Premium Feb 13, 2020 Genetron Health Obtains Regulatory Approval in China for NGS Instrument, Lung Cancer Panel Jan 22, 2020 Biocartis, AstraZeneca Expand Lung Cancer Biomarker Study With Master Collaboration Agreement Nov 21, 2019 Extrachromosomal Oncogene Amplification Involves Rearrangement of Regulatory Elements Sep 23, 2019 Global Survey Reveals Suboptimal Molecular Testing Access in Lung Cancer Despite Broad Guidelines Premium Aug 5, 2019 IncellDx Inks Chinese Collaboration, Distribution Agreements Jul 23, 2019 China's NMPA Extends Approval for Roche Cobas EGFR Mutation Test v2 to Plasma Samples Jul 18, 2019 Inivata to Test Liquid Biopsy Against Tissue Sequencing in French Prospective Clinical Trial Apr 10, 2019 Foundation Medicine, Flatiron Health Publish Clinical Validity of Clinico-Genomics Database Mar 4, 2019 Colon Cancer Patients Could Benefit From HER2 EGFR Non-Response Findings, Investigators Say Premium Jan 24, 2019 Memorial Sloan Kettering Using Cerebral Spinal Fluid Liquid Biopsy, Sequencing to Track Glioma Evolution Premium Jan 16, 2019 Qiagen EGFR Assay Approved in Japan as CDx to Pfizer NSCLC Drug Nov 29, 2018 Biocartis, AstraZeneca Partner on European Lung Cancer Biomarker Study Nov 20, 2018 EZLife, UCLA Team Aim to Expand EGFR Lung Cancer Assay Into RUO Offering Premium Nov 8, 2018 Biocartis Microsatellite Instability Assay Validated by MSKCC, Dartmouth Researchers Premium Load More Breaking News SUPER Psychosis Study Presented at ASHG Digs Into Relationships of Rare Variants, Phenotypes People in the News: New Appointments at Myriad Genetics, Becton Dickinson, Delfi Diagnostics, More In Brief This Week: Virginia Commonwealth University, Dovetail Genomics, Lucid Diagnostics, and More New Products Posted to GenomeWeb: Bio-Rad, PerkinElmer, Ares Genetics, Purigen Biosystems, More Genetron Health, Fosun Ink Commercialization Deal for Seq-MRD Test in China MultiMuTHER Team Tracks Expression, Metabolite Relationships in Aging TwinsUK Participants The Scan More Boosters for US Following US Food and Drug Administration authorization, the Centers for Disease Control and Prevention has endorsed booster doses of the Moderna and Johnson & Johnson SARS-CoV-2 vaccines, the Washington Post writes. From a Pig A genetically modified pig kidney was transplanted into a human without triggering an immune response, Reuters reports. For Privacy's Sake Wired reports that more US states are passing genetic privacy laws. Science Paper on How Poaching Drove Evolution in African Elephants In Science this week: poaching has led to the rapid evolution of tuskless African elephants.