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drug resistance

Examining more than half of its genome, researchers found the parasite's success is due to stripping its genome down to essential genes.

A small study of prostate cancers from African American and European American men uncovered ancestry-associated splicing with apparent ties to tumor aggressiveness and resistance.

A UK-led international consortium is sequencing tuberculosis genomes and cataloguing drug resistance mutations to enable more rapid NGS-based diagnostics.

Following treated leprosy patients, researchers saw three cases of recurrence that were classified as re-infection or relapse cases with genome sequences.

In Genome Biology this week: Mycobacterium tuberculosis population dynamics, mapping precision in GWAS, and more.

Ares plans to use the GEAR database to discover new markers of antibiotic resistance and will eventually develop it as an interpretation service. 

Researchers described a vancomycin-resistant Enterococcus infection transmitted from a liver donor to recipient, ruling out hospital-acquired infection with genomics.

Samples from metastatic melanoma patients treated sequentially with immunotherapies targeting CTLA4 and PD-1 pointed to response-related tumor features.

In Genome Research this week: algorithm to tease out strains from metagenomic sequences, drug resistance mechanisms in cancer cells, and more.

A retrospective analysis of Enterococcus faecium isolates from a UK hospital provided clues to infection sources and antibiotic resistance patterns.

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Politico reports that the NYPD DNA database has grown since it announced it would be removing profiles from it.

Forbes reports that a structural biology lab at Oxford University studying the coronavirus was hacked.

Science reports that a Dutch research funding agency is combating a ransomware attack.

In Science this week: set of 64 haplotype assemblies from 32 individuals, and more.