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Using sequencing from 262 drug-resistant Plasmodium falciparum representatives, researchers characterized the malaria parasite resistome.
Teams studying kidney and skin cancers independently implicated SWI/SNF chromatin remodeling mutations in checkpoint blockade immunotherapy response.
Investigators used sequencing, phylogenetics, and epidemiology to retrace transmission during a 2008 outbreak of carbapenem-resistant Klebsiella pneumoniae.
A genome-wide association study meta-analysis found bipolar disorder patients with poor response to lithium have more polygenic risk factors for schizophrenia.
The researchers found that most advanced EGFR-mutant lung cancer patients harbored changes in an average of two to three other oncogenes.
A pair of papers point to potential gut microbial contributions to checkpoint blockade immunotherapy response in individuals with lung, kidney, or skin cancer.
Alterations affecting the antigen presentation-related gene B2M appeared to be over-represented in melanomas with checkpoint blockade non-response or resistance.
Using genomic data from large cancer cell line collections, investigators identified versions of spliced genes that spell better or worse drug response.
In PNAS this week: host contributors to typhoid fever risk, effects of obesity-related variants near TMEM18, and more.
The Gaithersburg, Maryland-based firm intends to use the proceeds for general corporate purposes, including working capital and product development.
Politico reports that the NYPD DNA database has grown since it announced it would be removing profiles from it.
Forbes reports that a structural biology lab at Oxford University studying the coronavirus was hacked.
Science reports that a Dutch research funding agency is combating a ransomware attack.
In Science this week: set of 64 haplotype assemblies from 32 individuals, and more.