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drug resistance

Sequencing analysis of the Enterococcus faecium isolates found that they belonged to two clades, one of which harbored numerous resistance genes.

Researchers designed a PCR-based test for pyrethroid resistance based on a cytochrome P450 allele that is common in Anopheles funestus mosquitoes from Malawi.

In PNAS this week: numerous mobile genetic elements contribute to Vibrio cholerae drug resistance, troponin I mutations in sudden infant deaths, and more.

The new center will focus on liquid biopsy technologies for tracking treatment response and for monitoring patients with minimal residual disease.

Speed Search

Researchers from the University of Oxford have devised an approach to quickly search viral and bacterial genomes, according to the Atlantic.

The institutes will send patients samples to Resolution Bioscience, which will sequence circulating tumor DNA to identify the genetic causes of drug resistance.

In PNAS this week: sequencing analysis of Brooklyn measles cases, conserved neural transcriptional features that coincide with monogamy, and more.

The researchers also reported that combining an ER-directed therapy with an irreversible HER2 kinase inhibitor could overcome resistance.

In PLOS this week: similar variants seen in bullbogs, people with Robinow syndrome; ApoE genotypes in African-American, Puerto Rican populations; and more.

Researchers used genomic and transcriptomic data of isolates from seven Southeast Asian countries to find resistance-relevant pathways and expression quantitative trait loci.

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New analyses indicate the P.1 variant found in Brazil may be able to infect people who have already had COVID-19, the New York Times reports.

According to CNBC, Novavax's CEO says its vaccine could be authorized in the US as early as May.

The US National Institutes of Health has a new initiative to address structural racism in biomedical research.

In PNAS this week: GWAS of TLV-1-associated myelopathy/tropical spastic paraparesis, analysis of twins with hypertrophic cardiomyopathy, and more.