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drug resistance

Researchers used Mission Bio's Tapestri assay to identify and monitor the evolution of cancer mutations in acute myeloid leukemia in response to targeted treatment.

A new UK research center is to focus on preventing cancers from developing treatment resistance, New Scientist reports.

The test is the fourth assay on the firm's Revogene system and it detects five common genetic causes of drug resistance.

A CTC and ctDNA analysis suggests that the number of alterations affecting the androgen receptor can offer survival insights for TP53 mutation-free advanced cancer cases.

Mismatch repair-deficient tumors with many insertion-deletion mutations and enhanced microsatellite instability responded better to anti-PD-1 immunotherapy.

In PLOS this week: antibiotic resistance patterns in Escherichia coli, a dozen genetic loci tied to varicose vein risk, and more.

In Science this week: NASA Twins Study examines biological effects of a year in space, and more.

The PCR-based Carba assay is designed to detect and differentiate bacterial gene sequences that are associated with resistance to carbapenem antibiotics.

Researchers retraced transmission events and resistance contributors with whole-genome sequences for 100 carbapenem-resistant Klebsiella pneumoniae isolates from a Beijing hospital.

Researchers detected distinct antibiotic resistance patterns in untreated urban wastewater samples from northern and southern Europe.

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New analyses indicate the P.1 variant found in Brazil may be able to infect people who have already had COVID-19, the New York Times reports.

According to CNBC, Novavax's CEO says its vaccine could be authorized in the US as early as May.

The US National Institutes of Health has a new initiative to address structural racism in biomedical research.

In PNAS this week: GWAS of TLV-1-associated myelopathy/tropical spastic paraparesis, analysis of twins with hypertrophic cardiomyopathy, and more.