drug resistance
The multi-year project led by FIND is currently evaluating three end-to-end solutions through clinical studies.
Ovarian Cancer Chemotherapy Resistance Linked to Stress-Associated Gene Expression Features
By sequencing RNA in pre- and post-treatment cancer samples, researchers saw tumor and microenvironment features coinciding with poor neoadjuvant chemotherapy response.
Sequencing-Based MRD Detection in Bone Marrow May Predict ALL Relapse After CAR T-Cell Therapy
Researchers looked at relapse-related markers over time in pediatric and young adult acute lymphoblastic leukemia patients after CAR T-cell treatment.
New Research Consortium to Standardize Single-Cell Sequencing for Cancer Drug Resistance Studies
The main goal of the Persist-Seq private-public consortium is to generate a large single-cell cancer database in order to enable research on drug resistance.
WHO Updates Recommendations to Improve Access to Rapid MDx Tests for TB, Drug-Resistant TB
The WHO recommended moderate-complexity, automated nucleic acid amplification test for the initial detection of TB and resistance to rifampicin and isoniazid.