drug resistance

This Week in PNAS

In PNAS this week: sequencing analysis of Brooklyn measles cases, conserved neural transcriptional features that coincide with monogamy, and more.

The researchers also reported that combining an ER-directed therapy with an irreversible HER2 kinase inhibitor could overcome resistance.

This Week in PLOS

In PLOS this week: similar variants seen in bullbogs, people with Robinow syndrome; ApoE genotypes in African-American, Puerto Rican populations; and more.

Researchers used genomic and transcriptomic data of isolates from seven Southeast Asian countries to find resistance-relevant pathways and expression quantitative trait loci.

With long-read sequencing, mapping, and other approaches, researchers assembled a high-quality genome for Aedes aegypti, a notorious infectious disease vector.

This Week in PNAS

In PNAS this week: artemisinin resistance mutations in malaria parasites, ant-plant interactions over time, and more.

A team saw resilience and recolonization roles for antibiotic resistance gene-carrying microbes in the gut microbiomes of men treated with broad-spectrum antibiotics.

Members of the Beat AML consortium uncovered relationships between somatic mutations, gene expression profiles, and sensitivity to more than 100 drugs.

The PCR assay is intended to help detect TB-causing bacteria and determine if it harbors mutations associated with isoniazid and rifampicin resistance.

The amplicon sequencing method, called resistance mutation sequencing (RM-seq), may help in detecting resistance earlier than traditional techniques.

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Reuters reports that UK researchers are using gene-editing tools to develop flu-resistant chickens.

Nature calls for genomics to become part of the World Health Organization's cholera surveillance approach.

Vox explores a proposal to institute a lottery system to award grant funds.

In Genome Biology this week: gut microbiome study of individuals from Tanzania and Botswana, sixth version of the Network of Cancer Genes database, and more.