drug resistance

This Week in PNAS

In PNAS this week: host contributors to typhoid fever risk, effects of obesity-related variants near TMEM18, and more.

The Gaithersburg, Maryland-based firm intends to use the proceeds for general corporate purposes, including working capital and product development.

Examining more than half of its genome, researchers found the parasite's success is due to stripping its genome down to essential genes.

A small study of prostate cancers from African American and European American men uncovered ancestry-associated splicing with apparent ties to tumor aggressiveness and resistance.

A UK-led international consortium is sequencing tuberculosis genomes and cataloguing drug resistance mutations to enable more rapid NGS-based diagnostics.

Following treated leprosy patients, researchers saw three cases of recurrence that were classified as re-infection or relapse cases with genome sequences.

In Genome Biology this week: Mycobacterium tuberculosis population dynamics, mapping precision in GWAS, and more.

Ares plans to use the GEAR database to discover new markers of antibiotic resistance and will eventually develop it as an interpretation service. 

Researchers described a vancomycin-resistant Enterococcus infection transmitted from a liver donor to recipient, ruling out hospital-acquired infection with genomics.

Samples from metastatic melanoma patients treated sequentially with immunotherapies targeting CTLA4 and PD-1 pointed to response-related tumor features.

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NPR reports that Turkish high school students will no longer study evolution.

Researchers report they sequenced and identified plant species in an "al fresco" laboratory.

An Australian team searches for genetic alterations linked to depression in hopes of developing personalized treatments, the Sydney Morning Herald reports.

In PNAS this week: host contributors to typhoid fever risk, effects of obesity-related variants near TMEM18, and more.