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drug resistance

FIND Project Aims to Accelerate Targeted NGS Solutions for Global Drug-Resistant TB Testing
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The multi-year project led by FIND is currently evaluating three end-to-end solutions through clinical studies. 

Ovarian Cancer Chemotherapy Resistance Linked to Stress-Associated Gene Expression Features

By sequencing RNA in pre- and post-treatment cancer samples, researchers saw tumor and microenvironment features coinciding with poor neoadjuvant chemotherapy response.

Sequencing-Based MRD Detection in Bone Marrow May Predict ALL Relapse After CAR T-Cell Therapy

Researchers looked at relapse-related markers over time in pediatric and young adult acute lymphoblastic leukemia patients after CAR T-cell treatment.

New Research Consortium to Standardize Single-Cell Sequencing for Cancer Drug Resistance Studies

The main goal of the Persist-Seq private-public consortium is to generate a large single-cell cancer database in order to enable research on drug resistance.

WHO Updates Recommendations to Improve Access to Rapid MDx Tests for TB, Drug-Resistant TB

The WHO recommended moderate-complexity, automated nucleic acid amplification test for the initial detection of TB and resistance to rifampicin and isoniazid.

Jun 7, 2021

Antibiotic Resistance Genes in Gut Microbiome Rise After Travel Abroad, Study Finds

Jun 4, 2021

Breast Cancer Genomics Study Reveals Recurrent Contributors to Treatment Resistance in Early Disease

Apr 9, 2021

Enterobacteriaceae Pangenomes Offer Look at Antimicrobial Resistance Reservoirs in Natural Populations

Jan 19, 2021

OncoHost Raises $8 Million in Series B Funding Round

Oct 8, 2020

Genomic Data Helps Explain Yaws Re-emergence, Antibiotic Resistance in Papua New Guinea

Jul 17, 2020

Cepheid Debuts 10-Color Molecular Detection Technology With New Tuberculosis Test
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May 19, 2020

Advanced Biological Laboratories Gets CE-IVD Mark for HIV Genotyping Assays

Apr 15, 2020

Glioma Hypermutation May Not Correspond to Checkpoint Immunotherapy Response, Study Suggests

Apr 13, 2020

Analysis of Advanced, Metastatic Tumors Indicates How Treatment Influences Mutational Profiles

Apr 7, 2020

Blood-Based Genetic Risk Score Shows Promise for Prostate Cancer Drug Response, Survival Prediction
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Mar 9, 2020

Integrated Genomic Analysis Highlights Potential Strategy for Overcoming Some ALL Resistance

Jan 22, 2020

Single-Cell Expression Profiles Provide Treatment Clues in Drug Hypersensitivity Case

Jan 14, 2020

Asthma Drug Resistance Linked to Variant in Androgen Synthesis Gene

Jan 14, 2020

Immunotherapy Response Prediction Improves With TMB Correction, Other Markers
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Dec 16, 2019

Nanopore Sequencing Shows Promise for Rapid Diagnosis of Gut Condition in Preterm Infants
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Dec 9, 2019

PAK4 Inhibition Increases Anti-PD-1 Response in Mouse Models Prompting Phase I Trial

Nov 27, 2019

MRSA Study Details How Staph Is Transmitted Within Households

Nov 20, 2019

Host Expression Provides Treatment Response Clues in Cutaneous Leishmaniasis

Nov 14, 2019

Gene Screen Leads to Potential Malaria Targets in Liver-Stage Plasmodium Parasites

Nov 7, 2019

Colorectal Cancers Dial up Mutability in Response to Targeted Treatments

Breaking News
The Scan

UK Moves to Allow Sale of Gene-Edited Food

The UK is moving ahead to allow the sale of gene-edited food in England, Scotland, and Wales, according to New Scientist.

Questions for the Field

Stat News writes that the alleged Buffalo shooter's citation of genetics research raises questions about what the field can do.

Cell Studies on Tumor Evolution in Mouse Model of Lung Cancer, Stereo-seq, Bacteriophage Responses

In Cell this week: tumor evolution tracked in mouse model of lung cancer, organogenesis mapped using Stereo-seq, and more.

Taking Stock of the Stockpile

The US and European countries are evaluating their smallpox vaccine stockpiles as the number of monkeypox cases increases, the Washington Post reports.