CYP2D6 AMP-led Expert Groups Release Clinical CYP2D6 Pharmacogenomic Testing Recommendation The consensus guideline offers a two-tier categorization of alleles that are recommended for clinical CYP2D6 pharmacogenetic testing. University of Chicago Program Aims to Improve Knowledge Transfer for PGx Testing Premium The program uses an informatics system that converts genotype results to "traffic lights" telling clinicians whether a drug is acceptable for a certain patient. Tumor Heterozygosity Loss May Explain Failure of Studies to Link CYP2D6, Tamoxifen Benefit Premium Data shows CYP2D6 testing in breast tumor tissue can be inaccurate due to loss of heterozygosity, and may have obscured the connection between genotype and tamoxifen response in previous trials. Thermo Fisher Launches Digital PCR Application to ID Drug-Metabolizing Phenotypes Premium The new RUO application for the company's QuantStudio 3D Digital PCR platform is designed to enable researchers to accurately phenotype the CYP2D6 gene, a key indicator of drug metabolism. Does Lack of PGx Link in Recent Studies Foreshadow End of CYP2D6 Genotyping for Tamoxifen? Premium By Turna Ray Two recently published pharmacogenetic analyses looking at the impact of CYP2D6 alleles on tamoxifen response found no evidence that patients who harbor these mutations fail to respond to the hormone therapy. May 18, 2011 Medco to Evaluate Clinical Utility of AssureRx's PGx Test in Guiding Psychiatric Treatment Premium Dec 15, 2010 At SABCS, Presentations Highlight Ongoing Issues with Tamoxifen PGx Premium Nov 10, 2010 Doctor, Patient Adoption of PGx Testing Increases in PBM-Initiated Programs, Medco Reports at ASHG Premium Mar 10, 2010 AssureRx Updates GeneSightRx Panel with New Gene: CYP1A2 Premium Breaking News Eagle Biosciences, Genetic Analysis Ink Distribution Agreement for Gut Microbiota Test Centogene Q1 Revenues Grow More Than Fivefold Driven by COVID-19 Testing Epizyme Partnering With Quest for Lymphoma Mutation Testing Enzo Biochem, CLX Health Partner to Support COVID-19 Testing for International Travel Type 1 Diabetes GWAS, Fine-Mapping Leads to New Genetic Loci, Potential Drug Targets LSU Health Sciences Center Wins $2.4M to Lead SARS-CoV-2 Variant Sequencing Program The Scan Missed Early Cases A retrospective analysis of blood samples suggests early SARS-CoV-2 infections may have been missed in the US, the New York Times reports. Limited Journal Editor Diversity A survey finds low diversity among scientific and medical journal editors, according to The Scientist. How Much of a Threat? Science writes that need for a provision aimed at shoring up genomic data security within a new US bill is being questioned. PNAS Papers on Historic Helicobacter Spread, Brain Development, C. difficile RNAs In PNAS this week: Helicobacter genetic diversity gives insight into human migrations, gene expression patterns of brain development, and more.