CYP2D6
The company is seeing its CYP2C19 test adopted broadly as it prepares to submit a new application to the FDA for an assay targeting neurodegenerative disease.
PGx-Guided Dosing Can Lead to Faster Therapeutic Blood Levels of Antidepressants
A randomized controlled trial compared cytochrome P450 genotype-based dosing of tricyclic antidepressants to usual care among patients with depression.
Researchers have developed a computational method that considers uncommon CYP2D6 variants to assess patient-specific metabolism of tamoxifen and other drugs.
AMP-led Expert Groups Release Clinical CYP2D6 Pharmacogenomic Testing Recommendation
The consensus guideline offers a two-tier categorization of alleles that are recommended for clinical CYP2D6 pharmacogenetic testing.
The program uses an informatics system that converts genotype results to "traffic lights" telling clinicians whether a drug is acceptable for a certain patient.