CYP2D6 Sequencing-Based Assessment of CYP2D6 Could Improve Prediction of Drug Response Premium Researchers have developed a computational method that considers uncommon CYP2D6 variants to assess patient-specific metabolism of tamoxifen and other drugs. AMP-led Expert Groups Release Clinical CYP2D6 Pharmacogenomic Testing Recommendation The consensus guideline offers a two-tier categorization of alleles that are recommended for clinical CYP2D6 pharmacogenetic testing. University of Chicago Program Aims to Improve Knowledge Transfer for PGx Testing Premium The program uses an informatics system that converts genotype results to "traffic lights" telling clinicians whether a drug is acceptable for a certain patient. Tumor Heterozygosity Loss May Explain Failure of Studies to Link CYP2D6, Tamoxifen Benefit Premium Data shows CYP2D6 testing in breast tumor tissue can be inaccurate due to loss of heterozygosity, and may have obscured the connection between genotype and tamoxifen response in previous trials. Thermo Fisher Launches Digital PCR Application to ID Drug-Metabolizing Phenotypes Premium The new RUO application for the company's QuantStudio 3D Digital PCR platform is designed to enable researchers to accurately phenotype the CYP2D6 gene, a key indicator of drug metabolism. Mar 14, 2012 Does Lack of PGx Link in Recent Studies Foreshadow End of CYP2D6 Genotyping for Tamoxifen? Premium May 18, 2011 Medco to Evaluate Clinical Utility of AssureRx's PGx Test in Guiding Psychiatric Treatment Premium Dec 15, 2010 At SABCS, Presentations Highlight Ongoing Issues with Tamoxifen PGx Premium Nov 10, 2010 Doctor, Patient Adoption of PGx Testing Increases in PBM-Initiated Programs, Medco Reports at ASHG Premium Mar 10, 2010 AssureRx Updates GeneSightRx Panel with New Gene: CYP1A2 Premium Breaking News Delic Partners With GT Research for Genetic Analysis of Cannabis, Psychedelic Mushrooms Indivumed, Biognosys Expand Partnership to Offer Immunopeptidomics Insights Multiomic Study Identifies Drivers of Severe COVID-19 in Patients Under 50 Without Comorbidities Yourgene H1 2022 Revenues More Than Double Gencove Raises $10M in Series A Financing Blueprint Genetics, BioMarin to Offer Genetic Testing for Skeletal Dysplasia in Europe, Middle East The Scan Should've Been Spotted Sooner Scientists tell the Guardian that SARS-CoV-2 testing issues at a UK lab should have been noticed earlier. For Martian Fuel Researchers have outlined a plan to produce rocket fuel on Mars that uses a combination of sunlight, carbon dioxide, frozen water, cyanobacteria, and engineered E. coli, according to Gizmodo. To Boost Rapid Testing The Washington Post writes that new US programs aim to boost the availability of rapid at-home SARS-CoV-2 tests. PNAS Papers on Strawberry Evolution, Cell Cycle Regulators, False-Positive Triplex Gene Editing In PNAS this week: strawberry pan-genome, cell cycle-related roles for MDM2 and MDMX, and more.