CYP2D6 Sequencing-Based Assessment of CYP2D6 Could Improve Prediction of Drug Response Premium Researchers have developed a computational method that considers uncommon CYP2D6 variants to assess patient-specific metabolism of tamoxifen and other drugs. AMP-led Expert Groups Release Clinical CYP2D6 Pharmacogenomic Testing Recommendation The consensus guideline offers a two-tier categorization of alleles that are recommended for clinical CYP2D6 pharmacogenetic testing. University of Chicago Program Aims to Improve Knowledge Transfer for PGx Testing Premium The program uses an informatics system that converts genotype results to "traffic lights" telling clinicians whether a drug is acceptable for a certain patient. Tumor Heterozygosity Loss May Explain Failure of Studies to Link CYP2D6, Tamoxifen Benefit Premium Data shows CYP2D6 testing in breast tumor tissue can be inaccurate due to loss of heterozygosity, and may have obscured the connection between genotype and tamoxifen response in previous trials. Thermo Fisher Launches Digital PCR Application to ID Drug-Metabolizing Phenotypes Premium The new RUO application for the company's QuantStudio 3D Digital PCR platform is designed to enable researchers to accurately phenotype the CYP2D6 gene, a key indicator of drug metabolism. Mar 14, 2012 Does Lack of PGx Link in Recent Studies Foreshadow End of CYP2D6 Genotyping for Tamoxifen? Premium May 18, 2011 Medco to Evaluate Clinical Utility of AssureRx's PGx Test in Guiding Psychiatric Treatment Premium Dec 15, 2010 At SABCS, Presentations Highlight Ongoing Issues with Tamoxifen PGx Premium Nov 10, 2010 Doctor, Patient Adoption of PGx Testing Increases in PBM-Initiated Programs, Medco Reports at ASHG Premium Mar 10, 2010 AssureRx Updates GeneSightRx Panel with New Gene: CYP1A2 Premium Breaking News Canadian Healthcare Providers, Policymakers Value Different Aspects of Clinical Genomic Sequencing New Products Posted to GenomeWeb: Oxford Nanopore, Bio-Rad, NanoString, More People in the News at OraSure, Element Biosciences, Micronoma, More Guardant Health Files Motions to Dismiss, Change Venue in Illumina Patent Lawsuit In Brief This Week: SQI Diagnostics, T2 Biosystems, Enhanc3D, QuidelOrtho, More Illumina, Precision Health Research Singapore Partner for 100K Genomes Population Study The Scan Blend of Omicron With Delta The Associated Press reports that currently circulating Omicron variants have some features previously seen in the Delta variant. Limited Contrast The New York Times reports that there is a shortage of a contrast agent used for some medical scans. Pig Improvement Farmers in China are using genetics to improve their hog herds, according to Reuters. Science Papers Present Way to Molecularly Classify Prostate Cancer, Saliva-Based SARS-CoV-2 Test, More In Science this week: approach to molecularly classify prostate tumors, saliva-based test for SARS-CoV-2, and more.