CNVs

This Week in PLOS

In PLOS this week: genetic drift influences diversity among pathogens, QTLs linked to benzimidazole sensitivity, and more.

Investigators identified mutation, expression, and methylation differences in colorectal polyps from individuals with or without colorectal cancer.

An international team of researchers examined the scope and population specificity of copy-number variants affecting genes linked to drug metabolism.

The researchers said that their blood-based ddPCR assay could differentiate men with prostate cancer who have numerous copies of the androgen receptor gene.

Shared gastric adenocarcinoma tumor features seem to span geography and ethnicity, despite shifts in the proportion of tumors from different molecular subtypes.

Copy number changes affecting cancer-related genes appear to be prominent within and across tumors in individuals with colorectal cancer.

Using CNV profiles for more than 40,000 individuals with or without schizophrenia, researchers got a refined look at gains and losses linked to the condition.

A study by researchers in Austria suggests read depth patterns upstream of transcription start sites can provide clues to gene expression.

A re-analysis of non-invasive prenatal testing data from CARE found fewer false-positive cases caused by maternal copy number variants and other factors.

Three duplications appear to affect HOXB8 expression levels in the facial skin of chickens to give them a bearded look, researchers have found.

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University of California, San Diego, researchers have developed a gene drive to control a fruit-destroying fly.

A new study of a β-thalassemia gene therapy appears promising, according to NPR.

Futurism writes that gene doping could be the next generation of cheating in sports.

In Nature this week: hair color genes, hybridization between 13-year and 17-year cicadas, and more.