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The so-called '540 patent has been the focal point of a series of lawsuits between Sequenom and other NIPT firms since 2011. 

The company plans to move away from a centralized lab model to develop kits that can be used by any laboratory to perform its assays, focusing first on developing RUO kits and then clinical assay for lung cancer and more.

University of Leuven researchers reported that out of 4,000 noninvasive prenatal tests ran in prospective pregnancies, three yielded aberrant genome representations that were confirmed to be maternal cancer. 

With evidence of significant variation among consent procedures in the NIPT space, and the potential for a lack of awareness about incidental findings, Bianchi recommends the field come together to standardize procedures and education.

The reference standards will support CareDx's solid organ transplant injury monitoring diagnostic tests and be integrated into CLIA laboratory testing. 

The firm will discontinue its SensiGene Fetal RHD test.

If CareDx successfully commercializes its cfDNA tests, they would be the firm's first products since AlloMap launched in 2005.

The molecular diagnostics firm beat the consensus Wall Street estimate on the top line but missed it on the bottom line. 

The company is developing liquid biopsy tests to detect disease recurrence and drug resistance, but does not yet have a specific plan for its first commercial assay.

Royalty income drove the year-over-year revenue growth, but the firm still fell short of the consensus Wall Street estimate on the bottom line. 


At a meeting this week, researchers and others discussed the regulatory oversight needed for germline genome editing.

The US Food and Drug Administration has asked questions about Myriad Genetics' GeneSight test, according to Bloomberg.

Researchers report that neutrophil extracellular traps appear to binds gallstones together, according to New Scientist.

In Science this week: approach to infer genotype-by-environment interaction from genetic variants associated with phenotypic variability, and more.