A Winthrop-University Hospital team showed that demethylated circulating cell-free DNA from dying oligodendrocytes is a biomarker for relapsing-remitting MS.
The researchers said that this property of ctDNA could be exploited to improve the sensitivity of liquid biopsies.
In a pilot study, investigators identified infection-causing agents by sequencing microbial DNA in patient blood samples.
Based on data from more than 6,000 clinical cases, the investigators from Switzerland advocated for an expansion of NIPT to cover additional alterations and associated phenotypes.
The company's assay relies on proprietary methods of DNA isolation that enable analysis of cell-free DNA from finger-stick volume blood samples.
A New York University team used its maximum-depth sequencing method for profiling rare mutations in Escherichia coli in an unbiased manner.
The company plans to offer a test that analyzes genome-wide sequencing data using a machine learning engine to detect and characterize early cancers.
The company said it plans to publish its findings on its early-detection cancer tests, and will work with CMS and the FDA on pre-market review.
The funding will support development of tests that detect cell-free DNA methylation patterns indicative of disease in specific tissues of the body.
Natera said that a greater proportion of NIPTs for average-risk pregnancies are being reimbursed, while reimbursement for microdeletion testing is declining.
At a meeting this week, researchers and others discussed the regulatory oversight needed for germline genome editing.
The US Food and Drug Administration has asked questions about Myriad Genetics' GeneSight test, according to Bloomberg.
Researchers report that neutrophil extracellular traps appear to binds gallstones together, according to New Scientist.
In Science this week: approach to infer genotype-by-environment interaction from genetic variants associated with phenotypic variability, and more.