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cancer subtypes

NEW YORK (GenomeWeb) — A study of RNA-seq data from several Cancer Genome Atlas cohorts has found that patterns of pseudogene expression correspond strongly with several molecularly or clinically defined cancer subtypes and, in some cases, might offer additional subtyping or prognostic prediction

Researchers from the Dana Farber Cancer Institute have published results of a preliminary study tracking the patterns of mutations in the two histological subtypes of cervical cancer, which they are now planning to put to the test in a clinical trial of PI3 kinase inhibitors.

Researchers collaborating among a number of French institutions have developed and validated a novel gene-expression signature that classifies colon cancers into six distinct molecular subtypes with different pathological characteristics and varying prognoses.

Results from The Cancer Genome Atlas' analysis of several hundred endometrial cancers have classified the disease into four molecularly defined groups with differing prognoses.

Rosetta Genomics has published a study describing the development and initial validation of its miRview Kidney test, a 24-microRNA array-based assay that classifies a patient's primary kidney tumor into one of four main subtypes.

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Researchers tie a variant in ADAMTS3 to breathing difficulties in dissimilar dog breeds, according to Discover's D-brief blog.

The Japan Times reports that researchers sequenced the genome of a woman who lived during the Jomon period.

Parents of children with rare genetic disease have to contend with shifts in the interpretation of genetic variants, the Wall Street Journal reports.

In Science this week: single-nucleus RNA sequencing of brain tissue from individuals with autism, and more.