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cancer subtypes

Investigators have established hundreds of patient-derived xenografts, cell lines, and tumor samples, which appear to represent a wide range of melanoma molecular subtypes.

Using an integrated omics approach, researchers identified non-muscle invasive bladder cancer subtypes, along with pathways that are frequently altered in the disease.

Many molecularly distinct subgroups emerged from a meta-analysis bringing together more than 1,000 high-grade glioma or diffuse intrinsic pontine glioma cases.

The team found that cancer-causing genes depend on the BTK gene, which they believe they can shut down with an existing drug.

The Belgian company recently received €3.6 million to develop the signature into a clinical test within the next three years.

A new analysis hints that adenocarcinomas or squamous cell carcinomas may have certain overlapping expression patterns, regardless of the tissue of origin.

Researchers identified shifts in regulatory features and enhanced NOTCH signaling pathway activation in prostate tumors containing a TMPRSS2-ERG2 gene fusion.

Clustered mutation signatures in more than 1,000 tumors led to a process that appears to contribute to the development of some cancer driver mutations.

A recent JAMA Oncology study highlights the power of the open-access model GenomeDx has pursued since launching its Decipher prostate cancer prognostic. 

Investigators identified new recurrently mutated genes and overlap with other histological endometrial cancer subtypes by profiling more than a dozen CCEC cases.

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Rady Children's Institute for Genomic Medicine and Deloitte are looking into the use of drones to transport samples for testing. 

Direct-to-consumer genetic testing firm 23andMe is laying off about 100 people.

Researchers from Northwestern University examined dust for antibiotic-resistance genes, New Scientist reports. 

In Science this week: researchers present a computational method for predicting cellular differentiation state from single-cell RNA sequencing data, and more.