cancer subtypes
Cervical Cancer Multiomic Study Uncovers Informative Intratumor Heterogeneity States
With single-cell, spatial, and experimental approaches, researchers defined eight "meta-programs" linked to the tumor immune microenvironment and clinical features.
Machine Learning Cancer Prognostic Tool Identifies MYC Gain as Glioma Drug Resistance Marker
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The open-source CELLO2 algorithm helped identify a subset of glioma patients at high risk for developing resistance to Merck's Temodar (temozolomide).
Breast Cancer Risk Genes Unearthed in Exome Sequence Meta-Analysis
Researchers tracked down a handful of previously unappreciated susceptibility genes using exome sequences for more than 244,000 European women with or without breast cancer.
New Lung Cancer Evolution, Treatment Response Patterns Emerge From TRACERx Study
TRACERx researchers reported on non-small cell lung cancer features linked to disease progression, recurrence, treatment response, and more in seven new papers.
Breast Cancer Study Leads to New Susceptibility Gene, Potential Treatment Strategies
Researchers found risk variants in the DNA damage checkpoint gene ATRIP in a Polish founder population and linked the gene to breast cancer risk and HRD in other populations.