cancer subtypes ALL Genomes Marked by High DNA Methylation Levels Starting with samples from 82 pediatric cases of B-cell or T-cell acute lymphoblastic leukemia, researchers found widespread hypermethylation across ALL genomes. Breast Cancer Clues Revealed by Recurrent Tumor Microenvironment Structures Researchers identified 10 structures across almost 700 cases, including those with ties to cancer subtype, tumor alterations, and/or clinical outcomes. Ovarian Cancer Subtypes, Endometriosis Show Genetic Overlap in Study Endometriosis risk loci appeared to be linked to risk of specific epithelial ovarian cancer histotypes, with shared underlying processes and pathways. AML Proteogenomic Study Points to Prognostic Proteomic Subtypes An integrated analysis highlighted five proteomics-based subtypes, including a potentially targetable subtype showing poor outcomes on conventional treatment. Inherited Cancer Risk Detected in Significant Subset of Wilms Tumor Cases Researchers detected hereditary cancer susceptibility in around one-third of the Wilms tumor cases profiled in the Netherlands. Feb 23, 2022 Ovarian Cancer Chemotherapy Resistance Linked to Stress-Associated Gene Expression Features Feb 9, 2022 Large-Scale Cancer Genome Analysis Reveals Mutation Clusters That Can Inform Prognosis Jan 28, 2022 Breast Tumor Features Reflecting Germline Variants May Improve Risk Prediction Models Jan 27, 2022 Certain Childhood ALL Subtypes Linked to Genetic Ancestry Nov 17, 2021 Multiple Myeloma Patient Similarity Network Reveals Prognostically Informative Subgroups Oct 21, 2021 Germline Cancer Risk Genes May Hold Rhabdomyosarcoma Survival Clues, Study Suggests Oct 7, 2021 Lung Cancer Treatment Response Linked to Cancer-Associated Fibroblast Cell Subtypes Aug 5, 2021 Lung Cancer Features, Treatment Clues Emerge From 'Omic Analysis of Difficult-to-Treat Subtype Jun 4, 2021 Breast Cancer Genomics Study Reveals Recurrent Contributors to Treatment Resistance in Early Disease Feb 11, 2021 Glioblastoma Omics Study Highlights Informative Tumor Features, Immune Subtypes Jan 11, 2021 Glioblastoma Transcriptomes Point to Mitochondrial Subtype, Potential Treatment Strategies Dec 7, 2020 Neuroblastoma Super Enhancer Profiles Pinpoint Four Epigenetic Subtypes Nov 25, 2020 Pediatric Brain Tumor Proteomics Highlight Possible Treatment Targets, Biomarkers Oct 27, 2020 Clonal Hematopoiesis Mutation Study Reveals Risk of Treatment-Related Cancer Sep 17, 2020 Adrenal Neuroblastoma Cell Features Found by Single-Cell Transcriptome Sequencing Sep 4, 2020 Integrated Proteomic Study Leads to Metastasis, Response Clues in Chinese Colorectal Cancer Cases Aug 13, 2020 Triple-Negative Breast Cancer Treatment Hints Drawn From Single-Cell Study Jul 29, 2020 Pancreatic Cancer Action Network, GeneCentric Therapeutics Launch Research Partnership Jul 13, 2020 Metastatic Prostate Cancer Methylation Analysis Reveals Subtype, Ties to Driver Genes Jun 24, 2020 Stanford Team Debuts EPIC-Seq Method to Detect, Classify Cancer From cfDNA Fragment Patterns Load More Breaking News Canadian Healthcare Providers, Policymakers Value Different Aspects of Clinical Genomic Sequencing New Products Posted to GenomeWeb: Oxford Nanopore, Bio-Rad, NanoString, More People in the News at OraSure, Element Biosciences, Micronoma, More Guardant Health Files Motions to Dismiss, Change Venue in Illumina Patent Lawsuit In Brief This Week: SQI Diagnostics, T2 Biosystems, Enhanc3D, QuidelOrtho, More Illumina, Precision Health Research Singapore Partner for 100K Genomes Population Study The Scan Blend of Omicron With Delta The Associated Press reports that currently circulating Omicron variants have some features previously seen in the Delta variant. Limited Contrast The New York Times reports that there is a shortage of a contrast agent used for some medical scans. Pig Improvement Farmers in China are using genetics to improve their hog herds, according to Reuters. Science Papers Present Way to Molecularly Classify Prostate Cancer, Saliva-Based SARS-CoV-2 Test, More In Science this week: approach to molecularly classify prostate tumors, saliva-based test for SARS-CoV-2, and more.