cancer subtypes Germline Cancer Risk Genes May Hold Rhabdomyosarcoma Survival Clues, Study Suggests Research presented at ASHG suggested that germline cancer susceptibility profiling may help to predict survival outcomes for a subset of rhabdomyosarcoma cases. Lung Cancer Treatment Response Linked to Cancer-Associated Fibroblast Cell Subtypes Starting from NSCLC tumor samples, researchers identified three cancer-associated fibroblast subtypes with distinct molecular and treatment response features. Lung Cancer Features, Treatment Clues Emerge From 'Omic Analysis of Difficult-to-Treat Subtype With genomic, proteomic, transcriptomic, and other molecular data, investigators defined subtypes of lung squamous cell carcinoma and potential treatment targets or biomarkers. Breast Cancer Genomics Study Reveals Recurrent Contributors to Treatment Resistance in Early Disease Researchers saw convergent subclones crop up in early-stage, estrogen receptor-positive breast cancers that dodged endocrine- and CDK4/6 inhibitor-based therapies. Glioblastoma Omics Study Highlights Informative Tumor Features, Immune Subtypes Genomic, transcriptomic, proteomic, and post-transcriptional modification features in nearly 100 GBM tumors offered clues to tumor biology, revealing four immune subtypes. Jan 11, 2021 Glioblastoma Transcriptomes Point to Mitochondrial Subtype, Potential Treatment Strategies Dec 7, 2020 Neuroblastoma Super Enhancer Profiles Pinpoint Four Epigenetic Subtypes Nov 25, 2020 Pediatric Brain Tumor Proteomics Highlight Possible Treatment Targets, Biomarkers Oct 27, 2020 Clonal Hematopoiesis Mutation Study Reveals Risk of Treatment-Related Cancer Sep 17, 2020 Adrenal Neuroblastoma Cell Features Found by Single-Cell Transcriptome Sequencing Sep 4, 2020 Integrated Proteomic Study Leads to Metastasis, Response Clues in Chinese Colorectal Cancer Cases Aug 13, 2020 Triple-Negative Breast Cancer Treatment Hints Drawn From Single-Cell Study Jul 29, 2020 Pancreatic Cancer Action Network, GeneCentric Therapeutics Launch Research Partnership Jul 13, 2020 Metastatic Prostate Cancer Methylation Analysis Reveals Subtype, Ties to Driver Genes Jun 24, 2020 Stanford Team Debuts EPIC-Seq Method to Detect, Classify Cancer From cfDNA Fragment Patterns Jun 18, 2020 MMRF Taps GNS Healthcare to Analyze Multiple Myeloma Dataset Apr 3, 2020 Breast Cancer Subtypes Vary With Indigenous Ancestry in Latin American Women Dec 12, 2019 Proteomic Subtypes Identified in Pan-Cancer Analysis Nov 1, 2019 Breast Cancer Recurrence Risk Predicted by Immune-Related Germline Variants May 6, 2019 RB1 Alterations in Advanced Prostate Cancer Associated With Poor Outcome May 2, 2019 Immunotherapy Response in MMR-Deficient Tumors Linked to MSI Levels, Indel Mutations Apr 25, 2019 Colon Cancer Biology, Treatment Clues Found in Proteogenomic Analysis Apr 17, 2019 Non-Small Cell Lung Cancer Mutations, Tumor Microenvironment Profiled in China Apr 8, 2019 Proteome Analysis of Five Breast Tumor Subtypes Points to Additional Classifications Mar 29, 2019 Acute Erythroleukemia Genomic Subtypes Help Predict Outcomes, Suggest Therapies Load More Breaking News DNAe, Imperial College London, U of Leicester to Develop NGS-Based Breast Cancer Monitoring Test Illumina, Israel Ministry of Health to Pilot Genome Sequencing for Diagnosing Critically Ill Infants GenomSys Gains CE Mark for New Genomic Analysis Software Thermo Fisher Scientific Q3 Revenues up 9 Percent BTIG Initiates Coverage of LumiraDx With Buy Rating Delic Partners With GT Research for Genetic Analysis of Cannabis, Psychedelic Mushrooms The Scan Panel Recommends Pfizer-BioNTech Vaccine for Kids CNN reports that the US Food and Drug Administration advisory panel has voted in favor of authorizing the Pfizer-BioNTech SARS-CoV-2 vaccine for children between 5 and 11 years old. Sharing How to Make It Merck had granted a royalty-free license for its COVID-19 treatment to the Medicines Patent Pool, according to the New York Times. Bring it Back In Bloomberg reports that a genetic analysis has tied a cluster of melioidosis cases in the US to a now-recalled aromatherapy spray. Nucleic Acids Research Papers on SomaMutDB, VThunter, SCovid Databases In Nucleic Acids Research this week: database of somatic mutations in normal tissue, viral receptor-related expression signatures, and more.