cancer subtypes
Coding Variants in Five Breast Cancer Risk Genes Linked to Contralateral Breast Cancer
Researchers characterized contralateral breast cancer risk and breast cancer survival patterns associated with coding germline variants in known breast cancer-related genes.
Breast Cancer Outcomes Show Ties to Neighborhood Income in New Study
In estrogen receptor-positive breast cancer patients, lower income appeared to track with higher tumor expression-based recurrence scores, and shorter survival in the low-risk RS group.
Metastatic Tumor Subtypes Found With Expression Profiling
Researchers unearthed four metastatic tumor molecular subtypes based on gene expression profiles in patient-derived xenograft and human tumor samples.
Mutational Signatures Profiled in Pediatric Cancers
Researchers uncovered and analyzed mutational signatures in 27 cancer types or subtypes by analyzing genome sequences for nearly 800 tumors.
Immune Signatures Outperform TILs for HER2-Positive Breast Cancer Prognoses
Immune-related gene expression signatures tracked more closely with treatment response and outcomes than tumor-infiltrating lymphocytes in early-stage HER2-positive breast cancer.