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Jan 18, 2016

Tumor Cell, Mouse Studies Suggest c-Met Expression as Predictor of PARP Inhibitor Resistance

Researchers believe that blocking c-Met and PARP1 may help patients with TNBC, and possibly other cancers, overcome resistance to PARP inhibitors.

Sep 02, 2009

Pfizer, Abbott Ink Deal to Develop Companion Dx for PGx-based NSCLC Drug

Premium

Pfizer has previously touted PF-02341066 as "the first agent in clinical development that selectively targets a unique genetic feature of cancer cells." The drug is currently in Phase III trials, while Abbott is in the process of designing validating trials for a companion test with the capability to detect ALK gene rearrangements.

The Scan

Lamar Alexander Won't Seek Re-Election

 Senator Lamar Alexander (R-Tenn.), who chairs the Senate health committee, will be retiring at the end of his term, Stat News reports.

Second X Helping

UCSF researchers find that having two X chromosomes may contribute to women's longer lifespans, according to Discover's D-brief blog.

Tracing the Bugs

The Wall Street Journal reports on the US Centers for Disease Control and Prevention's use of genetic approaches to study foodborne illnesses.

This Week in PNAS

In PNAS this week: immune cell profiling of wild baboons by social status, metabolomics profiling of esophageal tumors, and more.

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