BRCA Biomarkers News and reporting on BRCA biomarkers. PLOS Papers on Orofacial Cleft Genetics, BRCA1/2 in Prostate Cancer in Morocco, More In PLOS this week: genetic contributors to cleft palate-related conditions, role of BRCA mutations in prostate cancer in Morocco, and more. Lynparza Benefit in Early BRCA-Mutated Breast Cancer Reignites Universal Genetic Testing Discussion Premium The OlympiA trial showed a disease-free survival benefit with adjuvant PARP inhibitor therapy for early-stage, BRCA1/2-mutated, HER2-negative breast cancer patients. For Reduced Recurrences According to the Guardian, a new study suggests treatment with a PARP inhibitor may decrease recurrences in hereditary breast cancer. BRCA2 Variants of Unknown Significance Reclassified Through Functional Data Additions Researchers reclassified 86 percent of variants initially determined to be VUS, potentially changing surveillance or treatment approaches for patients. Breast Cancer Risk Gene Associations Refined in Large-Scale Studies Two new studies revealed the prevalence of pathogenic variants in breast cancer-related genes, while highlighting genes that may be most informative in the clinic. Jul 27, 2020 Genetic Screening Identifies Many at Risk of Inherited Disease But Missed by Routine Care Jul 17, 2020 BRCA1/2 Population Screening Predicted to be Cost-Effective in Countries With Different Income Levels Jul 10, 2020 Study Sees Survival Boost For BRCA1/2 Carriers Tested Before Breast Cancer Diagnosis Jul 1, 2020 Polygenic Risk Score Modifies Breast Cancer Risk in Pathogenic Variant Carriers Jun 10, 2020 Cancer Experts Develop Precision Medicine-Based Genetic Testing Framework for Prostate Cancer Jun 4, 2020 Studies Show Potential of Video, Online Education to Expand Cancer Risk Genetic Test Access Premium May 31, 2020 Germline Results From Tumor-Normal Sequencing Guides Precision Therapy in Advanced Cancer Patients May 20, 2020 FDA Approves Lynparza With Myriad, Foundation Med CDx Tests in HRR-Mutated Prostate Cancer May 11, 2020 FDA Approves Lynparza/Avastin With Myriad Genetics CDx for Platinum-Sensitive Ovarian Cancer Apr 30, 2020 GSK Gets Broad Zejula Indication in Ovarian Cancer; FDA Deems Myriad Genetics' Test Complementary Apr 6, 2020 Myriad Genetics BRCA Test to be Reimbursed in Japan Feb 11, 2020 Myriad Files sPMA With FDA for Test to ID Best Responders to Lynparza, Avastin Combination Jan 29, 2020 Breast Cancer Risk Clues Found By Sequencing Cells From BRCA2 Germline Mutation Carriers Jan 21, 2020 Myriad Genetics Files for FDA Approval of BRACAnalysis CDx for Lynparza in Prostate Cancer Jan 8, 2020 Researchers Identify Breast Cancer Target Genes Via Fine-Mapping of Disease Risk Regions Dec 30, 2019 FDA Approves AstraZeneca's Lynparza, Myriad Genetics' CDx for BRCA-Positive Pancreatic Cancer Dec 12, 2019 Universal Genetic Testing in Breast Cancer May Result in More Harm Than Good, Experts Worry Premium Dec 12, 2019 ACMG Suggests Docs Evaluate All Breast Cancer Patients for Genetic Risk Test Suitability Dec 4, 2019 NCCN Updates Genetic Testing Guidelines for Assessing Breast, Ovarian, Pancreatic Cancer Risk Nov 21, 2019 Myriad Genetics BRACAnalysis Approved by Japanese Regulators Load More Breaking News In Brief This Week: Illumina, Personalis, Proteomedix, and More Ancient DNA Details Population Dynamics Within Andean Tiwanaku Civilization Genomic Data Spanning 2K Years Gives Glimpse of Etruscan Origins, Population Changes People in the News: New Appointments at Hologic, Akoya Biosciences, Caris Life Sciences, More At NSGC, Genetic Counselors Address Race-Based Medicine, Ways to Change New Products Posted to GenomeWeb: Becton Dickinson, Cosmos-ID, OncoDNA, More The Scan US Booster Eligibility Decision The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions. Arizona Bill Before Judge The Arizona Daily Star reports that a judge is weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction. Additional Genes Wales is rolling out new genetic testing service for cancer patients, according to BBC News. Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.