BRCA Biomarkers
Results from a homologous recombination deficiency assay concordance study led by Friends of Cancer Research were presented at the AMP annual meeting.
The company, infamous and long derided in the genetic testing community for refusing to share BRCA1/2 variants, has decided to change its stance as part of a "strategic transformation."
Single-Cell Sequencing Reveals Breast, Ovarian Cancer-Related Mutational Processes
Tracing structural variants and haplotype patterns in individual cells, researchers uncovered mutational processes that contribute to cancer formation, diversity, and evolution.
Breast Cancer Risk Contributors, Remaining Gaps Found With Familial Analyses
Segregation analyses focused on more than 17,400 breast cancer-affected families, highlighting age-related risk variants and yet-to-be-found recessive risk contributors.
Matched Therapy 'Evidence Scale' Predicts Targeted Treatment Efficacy in Breast Cancer Patients
With data from the SAFIR02-BREAST trial, researchers found patients with ESCAT I/II genomic alterations had longer progression-free survival when receiving a targeted therapy.