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Biology of Genomes

A speaker at this year's Biology of Genomes meeting discussed marrying genomics approaches such as CRISPR and single-cell sequencing to study disease causality.

Based on allele fragment sizes and mutational signatures, Europeans may have had shorter generation times than other populations, a Biology of Genomes speaker said.

The Bayesian Estimation of Variants in Regions tool estimates regional heritability using summary statistics from genome-wide association studies.

Apology for Toasting

Eric Lander has apologized for toasting Nobel laureate James Watson, who has espoused racist, sexist, and anti-Semitic views, Stat News reports.

Genome-wide association study hits can uncover potential therapies for conditions like inflammatory bowel disease, a Biology of Genomes speaker said.

A panel at the Biology of Genomes meeting discussed the ethical, legal, and social ramifications of germline gene editing.

Baylor College of Medicine's Olga Dudchenko sad the approach could assemble de novo mammalian genomes for less than $1,000.

In a talk at the meeting, Riken's Piero Carninci described the RADICL-seq tool he and his colleagues developed.

Stanford University's Eilon Sharon used CRISPeY to conduct a genome-wide precise editing study to study the fitness consequences of variants found in different yeast strains.

VC firm Andreessen Horowitz is putting big money into its second biology-focused investment fund in hopes of supporting engineering approaches to science.

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Kaiser Health News reports San Francisco and Alameda counties in California are no longer using Verily Life Sciences' COVID-19 testing program.

The New York Times reports that developers in New York City are increasingly interested in life science spaces.

A UK study has found that antibodies against SARS-CoV-2 may decline over time, Reuters reports.

In PNAS this week: genetic and epigenetic variation in individuals with diabetic kidney disease, spontaneous genetic alterations in Saccharomyces cerevisiae, and more.