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Biology of Genomes

A speaker at this year's Biology of Genomes meeting discussed marrying genomics approaches such as CRISPR and single-cell sequencing to study disease causality.

Based on allele fragment sizes and mutational signatures, Europeans may have had shorter generation times than other populations, a Biology of Genomes speaker said.

The Bayesian Estimation of Variants in Regions tool estimates regional heritability using summary statistics from genome-wide association studies.

Apology for Toasting

Eric Lander has apologized for toasting Nobel laureate James Watson, who has espoused racist, sexist, and anti-Semitic views, Stat News reports.

Genome-wide association study hits can uncover potential therapies for conditions like inflammatory bowel disease, a Biology of Genomes speaker said.

A panel at the Biology of Genomes meeting discussed the ethical, legal, and social ramifications of germline gene editing.

Baylor College of Medicine's Olga Dudchenko sad the approach could assemble de novo mammalian genomes for less than $1,000.

In a talk at the meeting, Riken's Piero Carninci described the RADICL-seq tool he and his colleagues developed.

Stanford University's Eilon Sharon used CRISPeY to conduct a genome-wide precise editing study to study the fitness consequences of variants found in different yeast strains.

VC firm Andreessen Horowitz is putting big money into its second biology-focused investment fund in hopes of supporting engineering approaches to science.

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Nature News reports on how meeting cancellations and related costs are affecting scientific societies.

In a new ruling, Canada's Supreme Court upheld the country's genetic non-discrimination law, the Canadian Press reports.

COVID-19 vaccine developers aim to avoid a complication that has affected efforts to develop vaccines for other diseases, the Wall Street Journal reports.

In PLOS this week: analysis of insertions throughout Shigella genomes, antigen production in malaria parasites, and more.