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Biology of Genomes

Combined Genomic Analyses Begin to Shed Light on Disease Causality

A speaker at this year's Biology of Genomes meeting discussed marrying genomics approaches such as CRISPR and single-cell sequencing to study disease causality.

Neanderthal Allele Fragment Size, Mutational Signatures Suggest Shorter European Generations

Based on allele fragment sizes and mutational signatures, Europeans may have had shorter generation times than other populations, a Biology of Genomes speaker said.

New Tool Described at Biology of Genomes Enables Local Heritability Estimates

The Bayesian Estimation of Variants in Regions tool estimates regional heritability using summary statistics from genome-wide association studies.

Genetic Variants Can Highlight Possible Drugs for Inflammatory Bowel Disease

Genome-wide association study hits can uncover potential therapies for conditions like inflammatory bowel disease, a Biology of Genomes speaker said.

ELSI Panel Dives Into Germline Gene Editing at Biology of Genomes

A panel at the Biology of Genomes meeting discussed the ethical, legal, and social ramifications of germline gene editing.