APOE4
Revvity Gets CE Mark for PCR Test Used to Guide Alzheimer's Therapy
Revvity's Euroimmun subsidiary has launched the EuroRealTime APOE assay in Europe for the detection and differentiation of common forms of the APOE gene.
Qiagen, Eli Lilly Collaborate on Alzheimer's Risk Dx Panel
The firms will develop a multiplex PCR panel for the QiaStat-Dx system that detects APOE genotypes.
Alzheimer's Disease Study Uncovers Presymptomatic Blood Protein Biomarkers
Researchers found pre-symptom protein markers for late-onset Alzheimer's disease, including proteins related to genetic disease risk, in participants of a prospective population study.
APOE4 Homozygosity Constitutes Genetic Form of Alzheimer's Disease, Study Suggests
Previously, having two copies of the APOE4 allele was merely regarded as raising the risk of developing Alzheimer's disease, not causative.
Late-Onset Alzheimer's Disease Features Thwarted by Protective Variant
A homozygous version of the Christchurch variant appeared to reduce disease-related features in mouse models and cells containing a late-onset Alzheimer's-linked APOE4 mutation.