APOE2
Revvity Gets CE Mark for PCR Test Used to Guide Alzheimer's Therapy
Revvity's Euroimmun subsidiary has launched the EuroRealTime APOE assay in Europe for the detection and differentiation of common forms of the APOE gene.
Qiagen, Eli Lilly Collaborate on Alzheimer's Risk Dx Panel
The firms will develop a multiplex PCR panel for the QiaStat-Dx system that detects APOE genotypes.
The company is seeing its CYP2C19 test adopted broadly as it prepares to submit a new application to the FDA for an assay targeting neurodegenerative disease.
APOE Missense Variant Linked to Increased Alzheimer's Disease Risk in African Americans
A case-control study found that the APOE ε3[R145C] variant, seen in 4 percent of African Americans, increases AD risk in individuals with the ε3/ε4 genotype.
Protective, Risk-Linked APOE Alleles Affect Glial Cell Transcriptome
The APOEε4 allele is linked to the upregulation of a phagocytosis and proinflammatory gene set both in normal aging and Alzheimer's disease brains.
Apr 20, 2011